Amjad Waseem, Qureshi Waqas, Farooq Ali, Sohail Umair, Khatoon Salma, Pervaiz Sarah, Narra Pratyusha, Hasan Syeda M, Ali Farman, Ullah Aman, Guttmann Steven
Forest Hills Hospital, Northshore-Long Island Jewish Health System.
Internal Medicine, Wake Forest Baptist Hospital.
Cureus. 2017 Sep 3;9(9):e1646. doi: 10.7759/cureus.1646.
Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal side effects. These side effects are the most common reasons for discontinuation of these drugs by the patients. Knowledge of these side effects is important for clinicians that manage antiarrhythmic drugs. This review focuses on the gastrointestinal side effects of these drugs and provides a detailed up-to-date literature review of the side effects of these drugs. The review provides case reports reported in the literature as well as possible mechanisms that lead to gastrointestinal side effects.
抗心律失常药物是常用的心脏药物。由于它们与胃肠道的几种受体存在受体模拟现象,常常会导致胃肠道副作用。这些副作用是患者停用这些药物的最常见原因。了解这些副作用对于管理抗心律失常药物的临床医生来说很重要。本综述聚焦于这些药物的胃肠道副作用,并提供了关于这些药物副作用的详细的最新文献综述。该综述提供了文献中报道的病例报告以及导致胃肠道副作用的可能机制。