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认知功能是瑞典多发性硬化症患者收入的主要决定因素,其独立于身体残疾。

Cognitive function is a major determinant of income among multiple sclerosis patients in Sweden acting independently from physical disability.

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden/Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Mult Scler. 2019 Jan;25(1):104-112. doi: 10.1177/1352458517740212. Epub 2017 Nov 16.

Abstract

BACKGROUND

In multiple sclerosis (MS), various aspects of cognitive function can be detrimentally affected, thus patients' employment and social functioning is commonly impacted.

OBJECTIVE

To analyse income among MS patients in relation to cognitive function, assessed with the Symbol Digit Modalities Test (SDMT).

METHODS

A cross-sectional study including 2080 MS patients was conducted linking national register-based data. Descriptive statistics and a two-part model were used to estimate differences in earnings and social benefits.

RESULTS

MS patients in the highest SDMT score quartile earned more than twice annually compared to patients in the lowest quartile, whereas patients in the lowest quartile received three times more income through social benefits. The difference in earnings and benefits across the SDMT performance quartiles remained statistically significant after adjusting for various clinical and socio-demographic variables, including physical disability. The corrected prevalence ratios for MS patients in the highest quartile for having income from earnings and benefits were 1.40 (95% confidence interval (CI): 1.29-1.49) and 0.81 (95% CI: 0.71-0.90), respectively, when compared to the patients in the lowest quartile.

CONCLUSION

Cognitive function affects the financial situation of MS patients negatively and independently of physical disability. This warrants cognitive testing as a routine measure in health care services for MS patients.

摘要

背景

在多发性硬化症(MS)中,认知功能的各个方面都可能受到不利影响,因此患者的就业和社会功能通常会受到影响。

目的

分析认知功能(用符号数字模态测验(SDMT)评估)与多发性硬化症患者收入之间的关系。

方法

进行了一项横断面研究,纳入了 2080 名多发性硬化症患者,并将全国基于登记的资料进行了关联。使用描述性统计和两部分模型来估计收入和社会福利方面的差异。

结果

与 SDMT 得分最低四分位的患者相比,得分最高四分位的 MS 患者年收入高出两倍以上,而得分最低四分位的患者通过社会福利获得的收入则高出三倍。调整了各种临床和社会人口统计学变量(包括身体残疾)后,SDMT 表现四分位数之间的收入和福利差异仍具有统计学意义。与最低四分位的患者相比,SDMT 得分最高四分位的 MS 患者中,收入来自工资和福利的校正患病率比分别为 1.40(95%置信区间(CI):1.29-1.49)和 0.81(95%CI:0.71-0.90)。

结论

认知功能对多发性硬化症患者的财务状况产生负面影响,且独立于身体残疾。这证明了认知测试作为多发性硬化症患者医疗服务的常规措施是合理的。

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