Palutke M, Tabaczka P, Varadachari C, Carrillo G
Br J Haematol. 1979 Nov;43(3):361-7. doi: 10.1111/j.1365-2141.1979.tb03763.x.
T lymphocytes, forming sheep erythrocyte rosettes at 37 degrees C, have been described in thymus glands, mitogen and allogeneic cell stimulated lymphocyte cultures, and acute T cell lymphoblastic leukaemia. This paper describes the finding of such lymphocytes in lymph nodes of a variety of disorders including Hodgkin's disease, Lennert's lymphoma, malignant lymphoma of large transformed T lymphocytes, immunoblastic lymphadenopathy, metastatic carcinoma, and other disorders. A large number of tonsils, but not reactive lymph nodes, also contained a significant number of those T lymphocytes. The significance of these findings in relation to interpretation of immune red cell rosettes and to the subclasses of T lymphocytes is discussed.
在37摄氏度下能形成绵羊红细胞花环的T淋巴细胞,已在胸腺、促有丝分裂原和同种异体细胞刺激的淋巴细胞培养物以及急性T细胞淋巴细胞白血病中有所描述。本文描述了在多种疾病的淋巴结中发现此类淋巴细胞,这些疾病包括霍奇金病、 Lennert淋巴瘤、大转化T淋巴细胞恶性淋巴瘤、免疫母细胞性淋巴结病、转移性癌及其他疾病。大量扁桃体含有相当数量的此类T淋巴细胞,但反应性淋巴结则不然。本文讨论了这些发现对于免疫红细胞花环解读及T淋巴细胞亚类的意义。