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Individualized intensified antiplatelet therapy based on platelet reactivity testing reduces the incidence of cardiovascular events in patients undergoing percutaneous coronary intervention.基于血小板反应性检测的个体化强化抗血小板治疗可降低接受经皮冠状动脉介入治疗患者的心血管事件发生率。
Anatol J Cardiol. 2017 Nov;18(5):376-377. doi: 10.14744/AnatolJCardiol.2017.8009.
2
Individualized dual antiplatelet therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials.经皮冠状动脉介入治疗患者基于血小板功能检测的个体化双联抗血小板治疗：随机对照试验的荟萃分析
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Efficacy and safety of intensified antiplatelet therapy on the basis of platelet reactivity testing in patients after percutaneous coronary intervention: systematic review and meta-analysis.基于血小板反应性检测的强化抗血小板治疗对经皮冠状动脉介入治疗后患者的疗效和安全性：系统评价和荟萃分析。
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Comparison of on-treatment platelet reactivity between triple antiplatelet therapy with cilostazol and standard dual antiplatelet therapy in patients undergoing coronary interventions: a meta-analysis.西洛他唑三联抗血小板治疗与标准双联抗血小板治疗在接受冠状动脉介入治疗患者中的治疗期血小板反应性比较：一项荟萃分析。
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Variability of platelet response to clopidogrel is not related to adverse cardiovascular events in patients with stable coronary artery disease undergoing percutaneous coronary intervention.接受经皮冠状动脉介入治疗的稳定型冠状动脉疾病患者中，血小板对氯吡格雷反应的变异性与不良心血管事件无关。
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A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI. Rationale and design of the Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (TROPICAL-ACS) Trial.一项关于接受经皮冠状动脉介入治疗（PCI）的急性冠状动脉综合征（ACS）患者血小板功能引导下抗血小板治疗降阶梯的随机试验。急性冠状动脉综合征慢性抗血小板治疗中血小板抑制反应性测试（TROPICAL-ACS）试验的原理与设计。
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本文引用的文献

1
Individualized dual antiplatelet therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials.经皮冠状动脉介入治疗患者基于血小板功能检测的个体化双联抗血小板治疗：随机对照试验的荟萃分析
BMC Cardiovasc Disord. 2017 Jun 15;17(1):157. doi: 10.1186/s12872-017-0582-6.
2
Association of measured platelet reactivity with changes in P2Y receptor inhibitor therapy and outcomes after myocardial infarction: Insights into routine clinical practice from the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) study.测量的血小板反应性与心肌梗死后P2Y受体抑制剂治疗变化及预后的关联：急性冠状动脉综合征后ADP受体抑制剂治疗：治疗模式和事件的纵向评估（TRANSLATE-ACS）研究对常规临床实践的启示
Am Heart J. 2017 May;187:19-28. doi: 10.1016/j.ahj.2017.02.003. Epub 2017 Feb 10.
3
Impact of high on-treatment platelet reactivity on long-term clinical events in AMI patients: a fact or mirage?高治疗期血小板反应性对急性心肌梗死患者长期临床事件的影响：事实还是幻象？
Anatol J Cardiol. 2017;17(2):E2. doi: 10.14744/AnatolJCardiol.2016.22626. Epub 2016 Nov 16.
4
2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).2014年欧洲心脏病学会/欧洲心胸外科学会心肌血运重建指南：欧洲心脏病学会（ESC）和欧洲心胸外科学会（EACTS）心肌血运重建特别工作组编写，欧洲经皮心血管介入协会（EAPCI）提供特别贡献。
Eur Heart J. 2014 Oct 1;35(37):2541-619. doi: 10.1093/eurheartj/ehu278. Epub 2014 Aug 29.
5
Optimizing P2Y12 receptor inhibition in patients with acute coronary syndrome on the basis of platelet function testing: impact of prasugrel and high-dose clopidogrel.基于血小板功能检测优化急性冠脉综合征患者的 P2Y12 受体抑制：普拉格雷和高剂量氯吡格雷的影响。
J Am Coll Cardiol. 2014 Mar 25;63(11):1061-70. doi: 10.1016/j.jacc.2013.12.023. Epub 2014 Jan 30.

Individualized intensified antiplatelet therapy based on platelet reactivity testing reduces the incidence of cardiovascular events in patients undergoing percutaneous coronary intervention.

作者信息

Spartalis Michael, Tzatzaki Eleni, Nikiteas Nikolaos I, Spartalis Eleftherios

机构信息

Division of Cardiology, Onassis Cardiac Surgery Center, Athens-Greece.

出版信息

Anatol J Cardiol. 2017 Nov;18(5):376-377. doi: 10.14744/AnatolJCardiol.2017.8009.

DOI:10.14744/AnatolJCardiol.2017.8009
PMID:29145223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5731292/
Abstract
摘要