Fu Tao, Wang Jing, Levin Moran, Xi Ping, Li Dongguo, Li Junfa
aBeijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, China bUniversity of Maryland Medical Center, Baltimore, MD cDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Medicine (Baltimore). 2017 Nov;96(46):e8528. doi: 10.1097/MD.0000000000008528.
Acute acquired comitant esotropia (AACE) is an unusual presentation of esotropia that occurs after infancy. This study was aimed to study the clinical features and the differences between children and adult patients with AACE in the Chinese populations.This was a retrospective analysis of patients diagnosed with AACE over 4 years; 69 patients (25 females and 44 males) were identified. The patients were divided into 3 groups: < 10 year-old (n = 6, 8.7%), 10-18 year-old (n = 23, 33.3%), and ≥18 year-old (n = 40, 58.0%). Patients underwent medical history, brain and orbital computed tomography, and ophthalmological and orthoptic examinations.The refractions of AACE patients varied among age groups: patients < 10 year-old had mild hypermetropia, while older children and adults showed moderate-to-high myopia (P < .001). The mean angles of esotropia were significantly larger in young children compared with older children and adults (P = .005). There was no significant difference in binocularity detected by either synoptophore or TNO stereoscopic testing among different disease durations. Stereopsis detected by synoptophore and TNO testing showed no significant difference at duration within half a year, but the stereopsis measured by TNO was significantly worse than that detected by synoptophore with extending disease duration (P < .05).AACE seems to occur mostly in older children and adults in the Chinese population. Younger children with AACE seem to demonstrate a common trait of mild hypermetropic refractive errors, while myopia can be seen in older children and adult patients. The duration from onset to treatment of esotropia does not affect the preoperative binocularity.
急性后天性共同性内斜视（AACE）是婴儿期后出现的一种不常见的内斜视表现。本研究旨在探讨中国人群中AACE患儿与成年患者的临床特征及差异。
这是一项对4年间诊断为AACE的患者进行的回顾性分析；共纳入69例患者（25例女性，44例男性）。患者分为3组：＜10岁组（n = 6，8.7%）、10 - 18岁组（n = 23，33.3%）和≥18岁组（n = 40，58.0%）。患者接受了病史采集、脑部和眼眶计算机断层扫描以及眼科和视光学检查。
AACE患者的屈光情况在不同年龄组有所不同：＜10岁的患者有轻度远视，而年龄较大的儿童和成人表现为中度至高度近视（P ＜.001）。幼儿的平均内斜角度明显大于年龄较大的儿童和成人（P = .005）。不同病程的患者通过同视机或TNO立体视检查检测到的双眼视功能无显著差异。同视机和TNO检查在病程半年内检测到的立体视无显著差异，但随着病程延长，TNO测量的立体视明显比同视机检测的差（P ＜.05）。
在中国人群中，AACE似乎大多发生于年龄较大的儿童和成人。患有AACE的幼儿似乎表现出轻度远视屈光不正的共同特征，而年龄较大的儿童和成年患者则可见近视。内斜视从发病到治疗的时间不影响术前双眼视功能。
