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妊娠和哺乳期相关性骨质疏松症患者的诊治:一例病例报告及文献综述

Approach to the patient with pregnancy and lactation-associated osteoporosis: A case report and a review of the literature.

作者信息

Zhang Min, Chen Ping, Li Bin, Du Juan, Pan Ting, Chen Jingyan

机构信息

aDepartment of Eldly Endocrinology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital bDepartment of Endocrinology, Zigong No. 4 People's Hospital, Sichuan, China.

出版信息

Medicine (Baltimore). 2017 Nov;96(46):e8671. doi: 10.1097/MD.0000000000008671.

Abstract

RATIONALE

Pregnancy and lactation-associated osteoporosis (PLO) is very rare, but it can cause severe vertebral compression fractures with disabling back pain. Although it is a rare, PLO must be kept in mind in the differential diagnosis in patients presenting with low back pain during or after pregnancy.

PATIENT CONCERNS

A 23-year-old woman who suffered from lumbago and fractures in the vertebral column 1 month after delivery.

DIAGNOSIS

Pregnancy and lactation-associated osteoporosis.

INTERVENTIONS

Combination therapy of calcium and vitamin D were used for treatment, as well as regular follow-up.

OUTCOMES

The patient's back pain had decreased significantly, the bone metabolic index, bone mineral density (BMD) had improved and she did not experience any recurrence.

LESSONS

Early diagnosis and treatment of calcium and vitamin D, as well as the efficacy of PLO intervention monitoring and evaluation are critical for the success of treatment.

摘要

理论依据

妊娠和哺乳期相关骨质疏松症(PLO)非常罕见,但可导致严重的椎体压缩性骨折并伴有致残性背痛。尽管PLO罕见,但在妊娠期间或产后出现腰痛的患者进行鉴别诊断时必须考虑到。

患者情况

一名23岁女性,产后1个月出现腰痛和脊柱骨折。

诊断

妊娠和哺乳期相关骨质疏松症。

干预措施

采用钙和维生素D联合治疗,并定期随访。

结果

患者背痛明显减轻,骨代谢指标、骨密度(BMD)有所改善,且未出现复发。

经验教训

钙和维生素D的早期诊断和治疗,以及对PLO干预的疗效监测和评估对治疗成功至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/5704841/8b0a56ab85bd/medi-96-e8671-g001.jpg

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