Haughey Lauren, Barbul Adrian
1 Tennessee Valley VA Hospital, Nashville, TN, USA.
2 Vanderbilt University School of Medicine, Nashville, TN, Vanderbilt University School of Medicine, Nashville, TN, USA.
Int J Low Extrem Wounds. 2017 Dec;16(4):238-243. doi: 10.1177/1534734617737639. Epub 2017 Nov 16.
The association between malnutrition, impaired wound healing, and the presence of chronic wounds has been recognized for a long time. It is widely believed that the lack of adequate nutrition increases the risk of developing wounds which have a great likelihood of progressing to chronicity due to lack of appropriate healing responses. This risk is particularly high in the aging population. For the individual patient, as well as patient populations, the diagnosis of malnutrition has been in dispute; further, there is lack of agreement of when and how to intervene nutritionally in those with wounds or healing deficits. This article examines the relationship of nutritional status with the presence and clinical evolution of leg ulcers in humans, focusing on diabetic and venous leg ulcers; we will further review the effect of nutritional therapy on the outcome of these ulcers.
营养不良、伤口愈合受损与慢性伤口的存在之间的关联早已为人所知。人们普遍认为，缺乏充足营养会增加伤口形成的风险，由于缺乏适当的愈合反应，这些伤口极有可能发展为慢性伤口。这种风险在老年人群中尤为高。对于个体患者以及患者群体而言，营养不良的诊断一直存在争议；此外，对于何时以及如何对有伤口或愈合缺陷的患者进行营养干预也缺乏共识。本文探讨营养状况与人类腿部溃疡的存在及临床演变之间的关系，重点关注糖尿病性和静脉性腿部溃疡；我们还将进一步回顾营养治疗对这些溃疡结局的影响。
