用于检测由mcr-1/mcr-2基因介导的多粘菌素耐药性的快速多粘菌素NP试验
Rapid Polymyxin NP test for the detection of polymyxin resistance mediated by the mcr-1/mcr-2 genes.
作者信息
Poirel Laurent, Larpin Yu, Dobias Jan, Stephan Roger, Decousser Jean-Winoc, Madec Jean-Yves, Nordmann Patrice
机构信息
Emerging Antibiotic Resistance, Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Fribourg, Switzerland; INSERM European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland; Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Switzerland.
Emerging Antibiotic Resistance, Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Fribourg, Switzerland; INSERM European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland.
出版信息
Diagn Microbiol Infect Dis. 2018 Jan;90(1):7-10. doi: 10.1016/j.diagmicrobio.2017.09.012. Epub 2017 Sep 22.
The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR-1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains either recovered from the environment, animals, or humans. Sensitivity and specificity were found to be 100%.
快速多粘菌素NP检测法是最近开发出来的，用于快速检测肠杆菌科细菌中的多粘菌素耐药性。在此，我们使用从环境、动物或人类中分离出的70株非冗余菌株，对该检测法检测产MCR-1/MCR-2肠杆菌科细菌的能力进行了评估。结果发现其敏感性和特异性均为100%。
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