Thomas Christopher, Khan Azhar, Khrishnan Hari, Das Gary
Department of Urology, Mayday University Hospital, Croydon, London, UK.
World J Oncol. 2010 Aug;1(4):176-178. doi: 10.4021/wjon222w. Epub 2010 Aug 29.
Medullary Renal Carcinoma is a rare, highly malignant neoplasm that originates in the renal medulla and typically affects young black patients with sickle cell trait. We report the case of a 17-year-old boy with a symptomatic left renal tumour. CT revealed that the mass originated from the kidney and was associated with a large para-aortic lymph node mass. Hemoglobin electrophoresis showed sickle cell trait and a needle biopsy confirmed the diagnosis of Renal Medullary Carcinoma. We discuss the obscurity and implications of such a diagnosis. It is essential that clinicians are aware of this diagnosis as any delay can be fatal in the outcome of this highly aggressive and extremely rare cancer.
肾髓质癌是一种罕见的高恶性肿瘤，起源于肾髓质，通常影响具有镰状细胞性状的年轻黑人患者。我们报告一例17岁有症状的左肾肿瘤男孩的病例。CT显示肿块起源于肾脏，并伴有一个大的主动脉旁淋巴结肿块。血红蛋白电泳显示镰状细胞性状，针吸活检确诊为肾髓质癌。我们讨论了这种诊断的模糊性及意义。临床医生必须了解这种诊断，因为对于这种极具侵袭性且极为罕见的癌症，任何延误都可能导致致命后果。
