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单发皮下结节作为非典型肺类癌的初始表现

Single Subcutaneous Nodule as Initial Presentation of Atypical Lung Carcinoid.

作者信息

Yu Run, Wolin Edward, Fan Xuemo

机构信息

Carcinoid and Neuroendocrine Tumor Center, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, USA.

出版信息

World J Oncol. 2010 Oct;1(5):204-207. doi: 10.4021/wjon246w. Epub 2010 Nov 2.

DOI:10.4021/wjon246w
PMID:29147207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649798/
Abstract

We report a 50-year-old woman whose atypical lung carcinoid presented as a single subcutaneous nodule. Biopsy of the nodule revealed neuroendocrine carcinoma likely from the lungs. Imaging studies revealed masses in lungs, pelvis and right axilla, and a seizure a few months later lead to discovery of brain metastasis. This case illustrates that an apparently innocuous subcutaneous nodule could be the initial presentation of an otherwise asymptomatic but widely metastatic atypical lung carcinoid. Physicians should be aware of signs of skin metastasis from lung malignancies and judiciously select patients with subcutaneous nodule for biopsy.

摘要

我们报告一名50岁女性，其非典型肺类癌表现为单个皮下结节。对该结节进行活检显示为可能源自肺部的神经内分泌癌。影像学检查发现肺部、骨盆和右腋窝有肿块，几个月后一次癫痫发作导致发现脑转移。该病例表明，一个看似无害的皮下结节可能是原本无症状但已发生广泛转移的非典型肺类癌的初始表现。医生应意识到肺部恶性肿瘤皮肤转移的迹象，并明智地选择皮下结节患者进行活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/731eafb47695/wjon-01-204-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/edc06e94d6df/wjon-01-204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/78fad454d811/wjon-01-204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/731eafb47695/wjon-01-204-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/edc06e94d6df/wjon-01-204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/78fad454d811/wjon-01-204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e38d/5649798/731eafb47695/wjon-01-204-g003.jpg

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Cutaneous Metastasis of Neuroendocrine Carcinoma with Unknown Primary Site: Case Report and Review of the Literature.原发部位不明的神经内分泌癌皮肤转移：病例报告及文献复习
Case Rep Dermatol. 2015 Oct 2;7(3):263-74. doi: 10.1159/000440661. eCollection 2015 Sep-Dec.
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An innocent appearing subcutaneous nodule diagnoses a small cell lung cancer in a never-smoker female.

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Update in pulmonary carcinoid tumors: a review article.肺类癌肿瘤的最新进展：一篇综述文章。
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