Oueida Zaher, Chirca Ioana, Gallinson David
Department of Internal Medicine, Morristown Memorial Hospital, 100 Madison Ave, Morristown, NJ 07962, USA.
Department of Hematology/Oncology, Morristown Memorial Hospital, 100 Madison Ave, Carol Cancer Center, Morristown, NJ 07962, USA.
World J Oncol. 2011 Apr;2(2):76-78. doi: 10.4021/wjon292e. Epub 2011 Apr 9.
We describe the case of a 27-year-old male with painful lymphadenopathy involving multiple sites. An excisional lymph node biopsy established the diagnosis of Kikuchi-Fujimoto disease (KFD) and the patient improved with supportive care only and did not have further episodes. This is a case of a rare, benign lymphadenitis, of unknown etiology. The histopathology proved the benign character of the lymphadenopathy and made the diagnosis clear, despite the nonspecific character of the clinical presentation. It is important to recognize the clinical and histopathological aspects of KFD in order to avoid unnecessary and sometimes harmful treatment, such as chemotherapy, when this disease is confounded with lymphoma.
我们描述了一名27岁男性的病例,其出现累及多个部位的疼痛性淋巴结病。切除性淋巴结活检确诊为菊池-藤本病(KFD),该患者仅通过支持治疗病情便有所改善,且未再复发。这是一例病因不明的罕见良性淋巴结炎病例。尽管临床表现不具特异性,但组织病理学证实了淋巴结病的良性特征并明确了诊断。认识KFD的临床和组织病理学特征很重要,这样在该疾病与淋巴瘤混淆时,可避免进行不必要的、有时甚至有害的治疗,如化疗。