Al Ghadeer Hussain A, AlKadhem Sajjad M, AlMajed Mohammed S, AlAmer Hassan M, AlHabeeb Jaber A, Alomran Suad H, AlMajed Abdullah S
Pediatrics, Maternity and Children Hospital, Al-Ahsa, SAU.
Pathology, Maternity and Children Hospital, Al-Ahsa, SAU.
Cureus. 2022 Jan 9;14(1):e21049. doi: 10.7759/cureus.21049. eCollection 2022 Jan.
Kikuchi-Fujimoto Disease (KFD) is a rare self-limiting condition of unknown etiology. It is characterized by fever, and lymphadenopathy most commonly involving posterior cervical lymph nodes. Although it is of uncertain etiology, it is associated with viral infections and autoimmune diseases. Distinction from lymphadenopathy-associated alternate disorders is crucial to avoid unneeded diagnostic procedures and treatment. KFD is diagnosed based on histopathologic examination of the excised lymph node. The management is supportive with favorable outcomes within a few weeks or months. In this case, we describe a 13-year-old boy who complained of painful cervical lymphadenopathy and fever for more than three weeks following COVID-19. Diagnostic workup has been established and KFD diagnosis made based on the histopathologic features of the involved lymph node. The patient showed complete recovery with no recurrence during follow-up. So, this case highlights the possible association between COVID-19 and KFD during this pandemic and keeping it in the differential diagnosis.
菊池-藤本病（KFD）是一种病因不明的罕见自限性疾病。其特征为发热，淋巴结病最常累及颈后淋巴结。尽管病因不明，但它与病毒感染和自身免疫性疾病有关。与淋巴结病相关的其他疾病相鉴别对于避免不必要的诊断程序和治疗至关重要。KFD通过切除淋巴结的组织病理学检查来诊断。治疗以支持治疗为主，数周或数月内预后良好。在此病例中，我们描述了一名13岁男孩，他在感染新冠病毒后出现颈部疼痛性淋巴结病和发热超过三周。已开展诊断检查，并根据受累淋巴结的组织病理学特征做出了KFD诊断。患者完全康复，随访期间无复发。因此，该病例凸显了在此次大流行期间新冠病毒与KFD之间可能存在的关联，并提示应将其纳入鉴别诊断。
