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一名新诊断为弥漫性大B细胞淋巴瘤患者的副肿瘤性坏死性脊髓病

Paraneoplastic Necrotizing Myelopathy in a Patient With Newly Diagnosed Diffuse Large B Cell Lymphoma.

作者信息

Lee Chau Hung, Bharwani Lavina, Sullivan Troy

机构信息

Department of Radiology, Tan Tock Seng Hospital,11 Jalan Tan Tock Seng, Singapore 308433.

John Hopkins Singapore International Medical Centre,11 Jalan Tan Tock Seng, Singapore 308433.

出版信息

World J Oncol. 2011 Aug;2(4):195-198. doi: 10.4021/wjon279w. Epub 2011 Aug 24.

DOI:10.4021/wjon279w
PMID:29147247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649658/
Abstract

Paraneoplastic neurological disorders are rare but particularly devastating forms of paraneoplastic syndromes, in part due to the fact that the entity is not usually considered as the initial differentials of a cancer patient presenting with neurological symptoms. We report a case of paraneoplastic necrotizing myelopathy associated with Diffuse Large B-cell Lymphoma in an elderly Chinese lady. After extensive investigations, the diagnosis was confirmed on spinal cord biopsy which showed extensive necrotic tissue and absence of tumour or vascular involvement.

摘要

副肿瘤性神经系统疾病是副肿瘤综合征中罕见但极具破坏性的形式，部分原因在于该实体通常不被视为出现神经系统症状的癌症患者的初始鉴别诊断。我们报告了一例老年中国女性中与弥漫性大B细胞淋巴瘤相关的副肿瘤性坏死性脊髓病。经过广泛检查，脊髓活检确诊了该疾病，活检显示有广泛的坏死组织，且无肿瘤或血管受累。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/fef5a15a9a53/wjon-02-195-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/d1e472652e02/wjon-02-195-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/8713638b04df/wjon-02-195-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/756f7e177161/wjon-02-195-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/fef5a15a9a53/wjon-02-195-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/d1e472652e02/wjon-02-195-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/8713638b04df/wjon-02-195-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/756f7e177161/wjon-02-195-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ad/5649658/fef5a15a9a53/wjon-02-195-g004.jpg

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