Kucukoner Mehmet, Inal Ali, Kaplan Mehmet Ali, Urakci Zuhat, Firat Ugur, Ucmak Feyzullah, Isikdogan Abdurrahman, Tekbas Guven
Medical Oncology Department, Dicle University, Diyarbakir, Turkey.
Pathology Department, Dicle University, Diyarbakir, Turkey.
World J Oncol. 2012 Jun;3(3):134-137. doi: 10.4021/wjon493w. Epub 2012 Jul 5.
Germ cell tumors (GCTs) occur generally in the testes or ovaries. Extra-gonadal location of GCTs is very rare .Extra-gonadal GCTs usually arise from midline structures, the commonest sites being the retroperitoneal and mediastinum. Gastrointestinal germ cell tumors are very uncommon. The etiology, prognosis and clinical course of gastrointestinal GCTs are not well understood yet. Weherein present two GCTs cases who referred with gastrointestinal bleeding and obstruction these tumors originated from retroperitoneal site. In the light of the literature, the clinical and pathological findings of the cases are presented. Prominent features of our cases were being located in the gastrointestinal system, being at young ages, presenting with gastrointestinal bleeding and good outcome.
生殖细胞肿瘤(GCTs)通常发生在睾丸或卵巢。GCTs的性腺外定位非常罕见。性腺外GCTs通常起源于中线结构,最常见的部位是腹膜后和纵隔。胃肠道生殖细胞肿瘤非常少见。胃肠道GCTs的病因、预后和临床过程尚未完全明确。在此,我们报告两例因胃肠道出血和梗阻就诊的GCTs病例,这些肿瘤起源于腹膜后部位。根据文献,介绍了病例的临床和病理表现。我们病例的突出特点是位于胃肠道系统、患者年龄较轻、表现为胃肠道出血且预后良好。