Salhan Divya, Sapkota Deepak, Verma Prakash, Kandel Saroj, Abdulfattah Omar, Lixon Antony, Zwenge Deribe, Schmidt Frances
Department of Pulmonary Medicine, Interfaith Medical Centre, Brooklyn, NY, USA.
J Community Hosp Intern Med Perspect. 2017 Oct 18;7(5):318-320. doi: 10.1080/20009666.2017.1374110. eCollection 2017.
Myxedema coma is a decompensated hypothyroidism which occurs due to long-standing, undiagnosed, or untreated hypothyroidism. Untreated hypothyroidism is known to affect almost all organs including the heart. It is associated with a decrease in cardiac output, stroke volume due to decreased myocardial contractility, and an increase in systemic vascular resistance. It can cause cardiac arrhythmias and the most commonly seen conduction abnormalities are sinus bradycardia, heart block, ventricular tachycardia, and torsade de pointes. The authors report a case of an elderly man who presented with sudden cardiac arrest and myxedema coma and who was successfully revived.
黏液性水肿昏迷是一种失代偿性甲状腺功能减退症,它是由长期未诊断或未治疗的甲状腺功能减退症引起的。已知未经治疗的甲状腺功能减退症几乎会影响包括心脏在内的所有器官。它与心输出量减少、由于心肌收缩力下降导致的每搏输出量减少以及全身血管阻力增加有关。它可引起心律失常,最常见的传导异常是窦性心动过缓、心脏传导阻滞、室性心动过速和尖端扭转型室速。作者报告了一例老年男性患者,该患者出现心脏骤停和黏液性水肿昏迷,最终成功复苏。