Jonasson Stina B, Hagell Peter, Hariz Gun-Marie, Iwarsson Susanne, Nilsson Maria H
Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Department of Neurology and Rehabilitation, Skåne University Hospital, Lund, Sweden.
Parkinsons Dis. 2017;2017:4151738. doi: 10.1155/2017/4151738. Epub 2017 Sep 25.
To evaluate a set of psychometric properties (i.e., data completeness, targeting, and external construct validity) of the Parkinson's disease Activities of Daily Living Scale (PADLS) in people with Parkinson's disease (PD). Specific attention was paid to the association between PADLS and PD severity, according to the Hoehn & Yahr (H&Y) staging.
The sample included 251 persons with PD (mean age 70 [SD 9] years). Data collection comprised a self-administered postal survey, structured interviews, and clinical assessments at home visits.
Data completeness was 99.6% and the mean PADLS score was 2.1. Floor and ceiling effects were 22% and 2%, respectively. PADLS scores were more strongly associated ( > 0.5) with perceived functional independence, ADL dependency, walking difficulties, and self-rated PD severity than with variables such as PD duration and cognitive function ( < 0.5). PADLS scores differed across H&Y stages (Kruskal-Wallis test, < 0.001). Those in H&Y stages IV-V had more ADL disability than those in stage III (Mann-Whitney test, < 0.001), whereas there were no significant differences between the other stages.
PADLS revealed excellent data completeness, acceptable targeting, and external construct validity. It seems to be well suited as a rough estimate of ADL disability in people with PD.
评估帕金森病日常生活活动量表（PADLS）在帕金森病（PD）患者中的一组心理测量学特性（即数据完整性、针对性和外部结构效度）。根据Hoehn & Yahr（H&Y）分期，特别关注PADLS与PD严重程度之间的关联。
样本包括251例PD患者（平均年龄70[标准差9]岁）。数据收集包括自行填写的邮寄调查问卷、结构化访谈以及家访时的临床评估。
数据完整性为99.6%，PADLS平均得分为2.1。地板效应和天花板效应分别为22%和2%。与PD病程和认知功能等变量（<0.5）相比，PADLS得分与感知功能独立性、日常生活活动依赖性、步行困难和自评PD严重程度的相关性更强（>0.5）。PADLS得分在H&Y各阶段存在差异（Kruskal-Wallis检验，<0.001）。H&Y分期为IV-V期的患者比III期患者有更多的日常生活活动能力障碍（Mann-Whitney检验，<0.001），而其他阶段之间无显著差异。
PADLS显示出优异的数据完整性、可接受的针对性和外部结构效度。它似乎非常适合作为PD患者日常生活活动能力障碍的粗略估计指标。
