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In reply.

作者信息

Wong Anselm, Landersdorfer Cornelia B, Graudins Andis

机构信息

School of Clinical Sciences, Department of Medicine, Monash University, Melbourne, Victoria, Australia.

Victorian Poisons Information Centre and Austin Toxicology Service, Austin Hospital, Heidelberg, Victoria, 3084, Australia.

出版信息

Eur J Clin Pharmacol. 2018 Feb;74(2):253. doi: 10.1007/s00228-017-2380-6. Epub 2017 Nov 16.

DOI:10.1007/s00228-017-2380-6
PMID:29147804
Abstract
摘要

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本文引用的文献

1
Analysis of an 8-hour acetylcysteine infusion protocol for repeated supratherapeutic ingestion (RSTI) of paracetamol.分析 8 小时乙酰半胱氨酸输注方案治疗反复超剂量摄入对乙酰氨基酚(RSTI)。
Clin Toxicol (Phila). 2018 Mar;56(3):199-203. doi: 10.1080/15563650.2017.1359620. Epub 2017 Aug 16.
2
Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning.用于对乙酰氨基酚中毒治疗的改良型乙酰半胱氨酸输注方案的药代动力学建模。
Eur J Clin Pharmacol. 2017 Sep;73(9):1103-1110. doi: 10.1007/s00228-017-2277-4. Epub 2017 Jun 17.
3
Risk prediction of hepatotoxicity in paracetamol poisoning.
对乙酰氨基酚中毒时肝毒性的风险预测
Clin Toxicol (Phila). 2017 Sep;55(8):879-892. doi: 10.1080/15563650.2017.1317349. Epub 2017 Apr 27.
4
Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine.尽管及时给予静脉注射乙酰半胱氨酸治疗,但入院时血浆对乙酰氨基酚浓度与肝损伤存在剂量依赖关系。
Clin Toxicol (Phila). 2016 Jun;54(5):405-10. doi: 10.3109/15563650.2016.1159309.
5
Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.静脉注射乙酰半胱氨酸治疗对乙酰氨基酚中毒的不良反应减少:一项随机对照试验。
Lancet. 2014 Feb 22;383(9918):697-704. doi: 10.1016/S0140-6736(13)62062-0. Epub 2013 Nov 28.
6
Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose.尽管早期静脉注射N-乙酰半胱氨酸治疗急性对乙酰氨基酚过量,但仍出现肝毒性。
Acad Emerg Med. 2009 Jan;16(1):34-9. doi: 10.1111/j.1553-2712.2008.00296.x. Epub 2008 Nov 8.