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[黏液罗氏菌所致双侧支气管肺炎]

[Bilateral bronchopneumonia due to Rothia mucilaginosa].

作者信息

De Escalante Yangüela B, Gracia Gutiérrez A, Gracia Tello B, Alastrué Del Castaño V, Bueno Juana E, Algárate Cajo S

机构信息

Hospital Clínico Universitario Lozano Blesa.

出版信息

An Sist Sanit Navar. 2017 Dec 29;40(3):479-483. doi: 10.23938/ASSN.0090.

Abstract

Rothia mucilaginosa (R. mucilaginosa), formerly named Stomatococcus mucilaginosus, is a facultatively anaerobic, encapsulated gram-positive coccus, which forms part of the normal oropharyngeal and is rarely considered to be a pathogen in immunocompetent patients, although it can produce, on rare occasions, serious infections like bacteremia, endocarditis and respiratory infections; such as pneumonia, pleural empyema or superinfection of bronchiectasis. We present the case of a 74-year-old male diagnosed with right basal pneumonia of torpid evolution with a poor initial response to different antibiotics, with clinical and radiological worsening and the appearance of bilateral bronchopneumonia with pseudonodular images. R. mucilaginosa in pure culture was isolated in three sputum cultures and in bronchial suction. The patient was finally treated with Linezolid with a good clinical response and normalisation of the thorax radiography, confirming the disappearance of R. mucilaginosa in subsequent sputum cultures. As there are few documented cases of pneumonia due to R. mucilaginosa, we believe that presenting this case will be of interest.

摘要

黏性罗氏菌(R. mucilaginosa),以前称为黏性口腔球菌,是一种兼性厌氧、有荚膜的革兰氏阳性球菌,它是正常口咽菌群的一部分,在免疫功能正常的患者中很少被认为是病原体,尽管在极少数情况下它会引发严重感染,如菌血症、心内膜炎和呼吸道感染;例如肺炎、胸腔积脓或支气管扩张症的重叠感染。我们报告一例74岁男性患者,诊断为进展缓慢的右肺基底肺炎,最初对不同抗生素反应不佳,临床和影像学表现恶化,出现双侧支气管肺炎伴假结节影像。在三次痰培养和支气管吸引物中分离出纯培养的黏性罗氏菌。患者最终接受利奈唑胺治疗,临床反应良好,胸部X线片恢复正常,后续痰培养证实黏性罗氏菌消失。由于黏性罗氏菌引起肺炎的病例报道较少,我们认为展示该病例将具有一定意义。

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