骶尾部畸胎瘤内发生的神经内分泌肿瘤引起的肢端肥大症和库欣综合征。
Acromegaly and Cushing's syndrome caused by a neuroendocrine tumor arising within a sacrococcygeal teratoma.
作者信息
Babiker Tarig, Kyrodimou Efstathia, Berney Daniel M, Gurnell Mark, Drake William M, Brooke Antonia
机构信息
Departments of Endocrinology and Histopathology Royal Devon and Exeter Hospital Barrack Road Exeter EX2 5DW UK.
Department of Histopathology Barts Cancer Institute Queen Mary, University of London London EC1A7BE UK.
出版信息
Clin Case Rep. 2017 Sep 14;5(11):1768-1771. doi: 10.1002/ccr3.1148. eCollection 2017 Nov.
A 60-year-old man with a pre-existing stable sacrococcygeal teratoma developed acromegaly, ectopic Cushing's syndrome, and 5HIAA secretion. To our knowledge, this represents the first reported case of ACTH and serotonin secretion, and likely GHRH or GH cosecretion, from a sacrococcygeal teratoma in an adult.
一名患有骶尾部成熟性畸胎瘤的60岁男性出现了肢端肥大症、异位库欣综合征和5-羟吲哚乙酸分泌。据我们所知，这是首例报道的成人骶尾部畸胎瘤分泌促肾上腺皮质激素和5-羟色胺，且可能同时分泌生长激素释放激素或生长激素的病例。
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