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儿童眼眶骨膜下脓肿的药物治疗

Medical management of orbital subperiosteal abscess in children.

作者信息

Rubin S E, Rubin L G, Zito J, Goldstein M N, Eng C

机构信息

Division of Ophthalmology, Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11042.

出版信息

J Pediatr Ophthalmol Strabismus. 1989 Jan-Feb;26(1):21-7. doi: 10.3928/0191-3913-19890101-06.

Abstract

The traditional treatment of subperiosteal orbital abscess consists of surgical drainage and antibiotic therapy. We successfully treated with antibiotics alone nine children (age range 26 months to 12 years) with clinical signs and symptoms of orbital cellulitis and computerized tomographic (CT) evidence of subperiosteal abscess and contiguous ethmoid sinusitis. Two additional patients successfully treated with nonsurgical therapy were identified retrospectively. All patients were admitted to the pediatric service with normal vision. Their visual function was assessed twice daily during the early stages of their illness. All patients improved with intravenous antibiotic therapy. One additional patient required surgical drainage for persistent pain after 1 week of slow but steady clinical improvement. All other patients were clinically cured with medical therapy alone. Five of the medical "cures" had posttreatment CT, which documented the resolution. No patient had a recurrence. We conclude that orbital subperiosteal abscess, like some other abscesses located elsewhere, may be amenable to non-surgical treatment, or that these patients may have had a phlegmon rather than an abscess and the currently accepted CT criteria for diagnosis of a subperiosteal abscess may require modification. We recommend that children with a subperiosteal abscess from contiguous ethmoidal sinusitis who have no evidence of compromised optic nerve function be given a trial of intravenous antibiotic therapy prior to consideration of surgical drainage.

摘要

传统的眶骨膜下脓肿治疗方法包括手术引流和抗生素治疗。我们仅用抗生素成功治疗了9名儿童(年龄范围为26个月至12岁),这些儿童有眶蜂窝织炎的临床体征和症状,以及眶骨膜下脓肿和相邻筛窦炎的计算机断层扫描(CT)证据。另外两名经非手术治疗成功的患者是回顾性确定的。所有患者入院时视力均正常。在疾病早期,每天对他们的视觉功能评估两次。所有患者经静脉抗生素治疗后均有改善。一名患者在临床缓慢但持续改善1周后,因持续疼痛需要手术引流。所有其他患者仅通过药物治疗临床治愈。5名经药物“治愈”的患者进行了治疗后的CT检查,结果显示病变已消退。没有患者复发。我们得出结论,眶骨膜下脓肿与其他一些位于其他部位的脓肿一样,可能适合非手术治疗,或者这些患者可能患有蜂窝织炎而非脓肿,目前公认的眶骨膜下脓肿CT诊断标准可能需要修改。我们建议,对于因相邻筛窦炎导致眶骨膜下脓肿且无视神经功能受损证据的儿童,在考虑手术引流之前,先进行静脉抗生素治疗试验。

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