Ball B A, Little T V, Weber J A, Woods G L
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
J Reprod Fertil. 1989 Jan;85(1):187-94. doi: 10.1530/jrf.0.0850187.
The estimated embryonic loss rate between Days 4 and 14 after ovulation for young, normal mares (9%) was significantly lower (P less than 0.01) than the estimated embryonic loss rate for aged subfertile mares (62%). Fertilization rates, which were based on the recovery of embryos at Day 4 after ovulation, were 96% and 81% (P less than 0.1) for normal and subfertile mares, respectively. Day-4 embryos were collected from the oviducts of normal and subfertile donors mares. These embryos were transferred to the uteri of synchronized, normal recipient mares to test the hypothesis that the high incidence of embryonic loss in subfertile mares was related to embryonic defects. The hypothesis was supported because embryo survival rates were significantly higher (P less than 0.05) for Day-4 embryos from normal compared to subfertile mares. These defects may have been intrinsic to the embryo or might have arisen due to the influence of the oviducal environment before Day 4 after ovulation.
排卵后4至14天，年轻、正常母马的胚胎损失率估计为9%，显著低于（P<0.01）老龄不育母马的胚胎损失率（62%）。基于排卵后第4天胚胎回收情况的受精率，正常母马和不育母马分别为96%和81%（P<0.1）。从正常和不育供体母马的输卵管中收集第4天的胚胎。将这些胚胎移植到同期的正常受体母马子宫内，以检验不育母马胚胎损失率高与胚胎缺陷有关这一假设。该假设得到了支持，因为与不育母马相比，正常母马第4天胚胎的存活率显著更高（P<0.05）。这些缺陷可能是胚胎固有的，也可能是由于排卵后第4天之前输卵管环境的影响而产生的。
