Filotico M, Filotico R
Department of Anatomic Pathology, Ospedale Fond. Card. Panico, Tricase (LE), Italy.
Dermatology Unit, Ospedale "Perrino", Brindisi, Italy.
Pathologica. 2017 Sep;109(3):143-147.
This report describes a case of kaposiform hemangioendothelioma arising in an adult man during the course of rheumatoid arthritis treated with steroids and methotrexate. The vascular proliferation began in the terminal phase of the disease, which culminated in acute renal failure and death. We discuss the possible relationship between rheumatoid arthritis, its treatment, and the onset of vascular proliferation, as well as the role of kaposiform hemangioendothelioma in aggravating the autoimmune disease and leading to its fatal outcome.
本报告描述了一例成年男性卡波西样血管内皮瘤病例,该患者在接受类固醇和甲氨蝶呤治疗类风湿关节炎的过程中发病。血管增生始于疾病终末期,最终导致急性肾衰竭和死亡。我们讨论了类风湿关节炎及其治疗与血管增生发作之间的可能关系,以及卡波西样血管内皮瘤在加重自身免疫性疾病并导致致命结局中所起的作用。