口腔卡波西样血管内皮瘤：一种罕见的发生于特殊部位的肿瘤。
Kaposiform Hemangioendothelioma of the Oral Cavity: A Rare Tumor with an Unusual Location.
机构信息
Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Molecular Pathology Area, Faculty of Dentistry, Universidad de la República, Montevideo, Uruguay.
出版信息
Head Neck Pathol. 2021 Dec;15(4):1421-1425. doi: 10.1007/s12105-021-01316-6. Epub 2021 Mar 13.
Abstract
Kaposiform hemangioendothelioma is a rare neoplasm with intermediate malignant behavior, mainly affecting infants and children. Involvement head and neck is uncommon, and there are only four cases reported in the oral cavity and oropharynx. Microscopically, it is characterized by a vascular proliferation permeated by spindle-to-ovoid cells resembling Kaposi sarcoma. Immunohistochemically, the tumor is positive for CD31, CD34 and negative for D2-40. Herein we present a rare case of intraoral Kaposiform hemangioendothelioma in a 10-year-old boy.
摘要
卡波西样血管内皮细胞瘤是一种罕见的具有中度恶性行为的肿瘤，主要发生于婴幼儿。头颈部受累并不常见，口腔和口咽仅有 4 例报道。镜下特点为梭形至椭圆形细胞弥漫性血管增生，类似于卡波西肉瘤。免疫组化染色肿瘤 CD31、CD34 阳性，D2-40 阴性。本文报道 1 例 10 岁男孩口腔卡波西样血管内皮细胞瘤。
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