Service de rhumatologie, hôpital Henri-Mondor, AP-HP, 94000 Créteil, France.
Service de rhumatologie, hôpital Henri-Mondor, AP-HP, 94000 Créteil, France; EA 7379, Epiderm E, université Paris Est-Créteil, 94010 Créteil, France.
Joint Bone Spine. 2018 Oct;85(5):537-544. doi: 10.1016/j.jbspin.2017.11.001. Epub 2017 Nov 16.
The therapeutic management of psoriatic arthritis has seen major changes over the last few years, as illustrated by the recent updates of the GRAPPA and EULAR recommendations. These changes were driven by new studies establishing important benefits from early management and tight control of disease activity. The concepts underlying the treatment of psoriatic arthritis must be reappraised in the light of these new data. The objectives of this review are to discuss new concepts, to describe and assess the new drug classes introduced for psoriatic arthritis and, whenever possible, to define the specific indications of each class based on the rheumatic disease phenotype and presence of extraarticular manifestations.
近年来，银屑病关节炎的治疗管理发生了重大变化，GRAPPA 和 EULAR 建议的最新更新就说明了这一点。这些变化是由新的研究推动的，这些研究证实了早期管理和严格控制疾病活动带来的重要益处。必须根据这些新数据重新评估治疗银屑病关节炎的基本概念。本文的目的是讨论新的概念，描述和评估新引入的银屑病关节炎药物类别，并尽可能根据风湿性疾病表型和关节外表现来确定每种类别的具体适应证。
