Scott Ryan T, McAlister Jeffrey E, Rigby Ryan B
The CORE Institute, 18444 North 25th Avenue, Suite 210, Phoenix, AZ 85023, USA.
The CORE Institute, 18444 North 25th Avenue, Suite 210, Phoenix, AZ 85023, USA.
Clin Podiatr Med Surg. 2018 Jan;35(1):37-52. doi: 10.1016/j.cpm.2017.08.008. Epub 2017 Oct 19.
Arthrodesis of the ankle or foot is a common procedure for chronic pain and disability. Nonunion remains a prevalent complication among arthrodesis procedures. Some patients present with an inherent risk of developing a nonunion. Allograft biologics have gained popularity in an effort to reduce complications such as nonunion. Various biologics bring unique properties while maintaining a singular purpose. Platelet-derived growth factor (PDGF) may be introduced into a fusion site to facilitate healthy bony consolidation. The purpose of this article is to review the benefits and modalities of PDGF and how it can improve patient outcomes in ankle and hindfoot fusions.
踝关节或足部关节融合术是治疗慢性疼痛和残疾的常见手术。骨不连仍是关节融合术常见的并发症。一些患者存在发生骨不连的固有风险。同种异体生物制剂为减少诸如骨不连等并发症而受到欢迎。各种生物制剂具有独特特性，同时保持单一用途。血小板衍生生长因子（PDGF）可引入融合部位以促进健康的骨愈合。本文旨在综述PDGF的益处和应用方式，以及它如何改善踝关节和后足融合术的患者预后。
