Xu Yan-Min, Zhong Bao-Liang, Chen Wen-Cai, Zhu Jun-Hong, Lu Jin
Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science & Technology, Wuhan, Hubei Province, China.
Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
Oncotarget. 2017 Sep 16;8(49):86181-86187. doi: 10.18632/oncotarget.21032. eCollection 2017 Oct 17.
Heroin users are at high risk for suicide. However, the epidemiological profile of suicidal behaviors in Chinese methadone-maintained patients remains largely unknown. This study determined the prevalence and correlates of suicidal ideation among Chinese methadone-maintained patients. A total of 603 methadone-maintained patients were consecutively recruited from three methadone maintenance treatment (MMT) clinics in Wuhan, China, and administered with standardized questionnaires to collect sociodemographic, clinical, and psychological data. Suicidal ideation was measured with a single self-report question "Have you ever thought about committing suicide?". Depression and anxiety were assessed with Zung's Self-rating Depression Scale and Zung's Self-rating Anxiety Scale, respectively. The one-month and lifetime prevalence rates of suicidal ideation were 17.9% and 58.9%, respectively. In multiple logistic regression, lifetime suicidal ideation was significantly associated with female (OR: 1.69), an educational attainment of primary school and below (OR: 1.47), fair and poor interpersonal relationship (OR: 2.20), a history of injecting heroin (OR: 1.60), depression (OR: 1.38), and anxiety (OR: 4.00). Methadone-maintained patients of MMT clinics have a high prevalence of suicidal ideation and therefore at high risk for suicide. Suicide prevention efforts at MMT clinics should include periodic evaluation of suicidality, psychosocial supports, and, when necessary, psychiatric treatment and crisis intervention.
海洛因使用者有很高的自杀风险。然而,中国美沙酮维持治疗患者自杀行为的流行病学特征在很大程度上仍不为人知。本研究确定了中国美沙酮维持治疗患者自杀意念的患病率及其相关因素。在中国武汉的三家美沙酮维持治疗(MMT)诊所连续招募了603名美沙酮维持治疗患者,并对他们进行标准化问卷调查,以收集社会人口学、临床和心理数据。自杀意念通过一个自我报告问题“你是否曾想过自杀?”来衡量。抑郁和焦虑分别采用zung氏自评抑郁量表和zung氏自评焦虑量表进行评估。自杀意念的一个月患病率和终生患病率分别为17.9%和58.9%。在多因素logistic回归分析中,终生自杀意念与女性(比值比:1.69)、小学及以下文化程度(比值比:1.47)、人际关系一般和较差(比值比:2.20)、有注射海洛因史(比值比:1.60)、抑郁(比值比:1.38)和焦虑(比值比:4.00)显著相关。MMT诊所的美沙酮维持治疗患者自杀意念患病率很高,因此自杀风险也很高。MMT诊所的自杀预防工作应包括定期评估自杀倾向、提供社会心理支持,必要时进行精神科治疗和危机干预。