Macera M J, Babu A, Verma R S
Division of Genetics, Long Island College Hospital, Brooklyn, N.Y.
Oncology. 1989;46(1):61-2. doi: 10.1159/000226683.
The recent advent of banding techniques has facilitated the identification of human chromosomal abnormalities in neoplasias. Utilization of a single technique for the identification of marker chromosomes has caused ambiguity because staining profiles overlap with many other chromosomal regions in the human genome. Thus, the implication of DA/DAPI technique in clinical cytogenetics has been documented by presenting a variety of cases with neoplastic syndromes.
带型技术的近期出现促进了肿瘤中人类染色体异常的识别。使用单一技术识别标记染色体已造成了模糊性,因为染色图谱与人类基因组中的许多其他染色体区域重叠。因此,通过呈现各种肿瘤综合征病例,已证明了DA/DAPI技术在临床细胞遗传学中的意义。