Klinik für Radiologie, Charité - Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, D -10117, Berlin, Germany.
Department of Internal Medicine I, Division of Cardiology, Pneumology, Angiology and Intensive Medical Care, University Hospital Jena, Friedrich Schiller University Jena, Jena, Germany.
ESC Heart Fail. 2018 Feb;5(1):3-8. doi: 10.1002/ehf2.12236. Epub 2017 Nov 21.
Coronary artery disease (CAD) is a major risk factor for the incidence and progression of heart failure (HF). HF is characterized by a substantial morbidity and mortality and its lifetime risk is estimated at approximately 20% for men and women. As patients are in most cases identified only after developing overt clinical symptoms, detecting early stages of CAD and HF is of paramount importance. Due to its non-invasiveness, excellent soft-tissue contrast, high spatial resolution, and multiparametric nature, cardiovascular magnetic resonance (CMR) imaging has emerged as a promising radiation-free technique to assess a wide range of cardiovascular diseases such as CAD or HF, enabling a comprehensive evaluation of myocardial anatomy, regional and global function, and viability with the additional benefit of in vivo tissue characterization. CMR has the potential to enhance our understanding of coronary atherosclerosis and the aetiology of HF on functional and biological levels, to identify patients at risk for CAD or HF, and to enable individualized patient management and improved outcomes. Even though larger-scale studies on the different applications of CMR for the assessment of heart failure are scarce, recent research highlighted new possible clinical applications for CMR in the evaluation of CAD and HF.
冠心病（CAD）是心力衰竭（HF）发生和进展的主要危险因素。HF 具有较高的发病率和死亡率，其终生风险估计男性约为 20%，女性约为 20%。由于大多数患者只有在出现明显临床症状后才被确诊，因此早期发现 CAD 和 HF 至关重要。由于心血管磁共振（CMR）成像具有非侵入性、出色的软组织对比、高空间分辨率和多参数特性，因此已成为一种很有前途的无辐射技术，可以评估广泛的心血管疾病，如 CAD 或 HF，能够全面评估心肌解剖结构、局部和整体功能以及活力，同时还具有体内组织特征的优势。CMR 有潜力提高我们对冠状动脉粥样硬化和 HF 在功能和生物学水平上的病因的理解，以识别有 CAD 或 HF 风险的患者，并实现个体化的患者管理和改善预后。尽管关于 CMR 在心力衰竭评估中的不同应用的更大规模研究很少，但最近的研究强调了 CMR 在 CAD 和 HF 评估中的新的可能的临床应用。
