Russell I J
Department of Medicine, University of Texas Health Science Center, San Antonio.
Rheum Dis Clin North Am. 1989 Feb;15(1):149-68.
There is a growing awareness that fibrositis/fibromyalgia syndrome is a systemic disorder for which a pathogenic mechanism must be sought. A generalized deficiency of the neurotransmitter, serotonin could explain many of fibromyalgia's typical manifestations. The serotonin deficiency hypothesis is appealing because it provides a number of experimental approaches that can now be used to further study the pathogenesis of this disorder.
越来越多的人意识到纤维织炎/纤维肌痛综合征是一种全身性疾病，必须探寻其发病机制。神经递质血清素的普遍缺乏可以解释纤维肌痛的许多典型表现。血清素缺乏假说很有吸引力，因为它提供了一些实验方法，现在可用于进一步研究这种疾病的发病机制。
