Tang Jie, Tang Xianglong, Li Zhenhua, Liu Yikang, Tan SongHua, Li Heng, Ke RongDan, Wang Zhi, Gong Li, Tang AnZhou
Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Guangxi, Nanning 530000, People's Republic of China.
Anat Rec (Hoboken). 2018 Jun;301(6):1086-1095. doi: 10.1002/ar.23730. Epub 2018 Feb 21.
Understanding the anatomical variations in the human cochlea is important for cochlear implants. This study examined these variations using a reconstructed fusion model of the skull and temporal bone. The three-dimensional (3D) digital model of the temporal bone was reconstructed from multiple axial micro-computed tomography (CT) scans of temporal bone and high resolution CT of the skull from 15 cadavers. A skull model was reconstructed and merged with the reconstructed temporal bone. The 3D relationship between the cochlea and the skull's mid-sagittal plane was analyzed. The α and β angles of the cochlear autogenous rotation and bottom position, respectively, further subdivided the cochlear spatial orientation. The relationship between the base of the cochlea and the round window was evaluated with the Φ angle. Cochlear size was measured and the relationship was statistically analyzed. Cochlear implant electrode arrays were observed in five cases of right-temporal bone specimens. The α, β, and Φ angles were 46.01 ± 9.65, 56.79 ± 3.58, and 44.41 ± 7.23, respectively. The α angle varied greatly and was negatively correlated to the Φ angle (correlation coefficient = -0.211, P < 0.05). Among the five specimens, the α and Φ angle of the 2R and 4R cochlear specimens was lower and higher than the mean value, respectively. These measurements revealed variations in the size and position of the cochlea. Some of these variations may require surgical adjustments for insertion of electrodes with cochlear implants and present a greater challenge for implantation of cochlear electrode implantation. These data also provide a better understanding of variations in human cochlear anatomy. Anat Rec, 301:1086-1095, 2018. © 2017 Wiley Periodicals, Inc.
了解人类耳蜗的解剖变异对于人工耳蜗植入很重要。本研究使用头骨和颞骨的重建融合模型来检查这些变异。颞骨的三维（3D）数字模型是从15具尸体的颞骨多轴微计算机断层扫描（CT）和头骨的高分辨率CT重建而来的。重建了一个头骨模型并与重建的颞骨合并。分析了耳蜗与头骨正中矢状面之间的3D关系。耳蜗自身旋转的α角和底部位置的β角进一步细分了耳蜗的空间方向。用Φ角评估耳蜗底部与圆窗之间的关系。测量了耳蜗大小并进行了统计学分析。在5例右侧颞骨标本中观察了人工耳蜗电极阵列。α、β和Φ角分别为46.01±9.65、56.79±3.58和44.41±7.23。α角变化很大，且与Φ角呈负相关（相关系数=-0.211，P<0.05）。在这5个标本中，2R和4R耳蜗标本的α角和Φ角分别低于和高于平均值。这些测量揭示了耳蜗大小和位置的变异。其中一些变异可能需要在人工耳蜗植入电极时进行手术调整，并且对人工耳蜗电极植入构成了更大的挑战。这些数据也有助于更好地理解人类耳蜗解剖结构的变异。《解剖学记录》，301:1086-1095，2018年。©2017威利期刊公司。
