Zou Jing, Lähelmä Jaakko, Koivisto Juha, Dhanasingh Anandhan, Jolly Claude, Aarnisalo Antti, Wolff Jan, Pyykkö Ilmari
Hearing and Balance Research Unit, Field of Oto-laryngology, School of Medicine, University of Tampere , Tampere , Finland.
Acta Otolaryngol. 2015 May;135(5):466-72. doi: 10.3109/00016489.2014.993090. Epub 2015 Feb 13.
The present experimental set-up of high spatial resolution cone-beam computed tomography (CBCT) showed advantages of demonstrating the critical landmarks of the cochlea in identifying the position of intracochlear electrode contacts and has the potential for clinical application in cochlear implant (CI) surgery.
To evaluate a newly developed CBCT system in defining CI electrode array in human temporal bone and cochlear morphological variation.
Standard electrode, flexible tip electrode (Flex28), and an experimental electrode array with 36 contacts from MED-EL were implanted into the cochleae of six human temporal bones through an atraumatic round window membrane insertion. The cochleae were imaged with 900 frames using an experimental set-up based on a CBCT scanner installed with Superior SXR 130-15-0.5 X-ray tube in combination with filtration of copper and aluminum.
In all temporal bones, the landmarks of the cochlea, modiolus, osseous spiral lamina, round window niche, and stapes were demonstrated at an average level of 3.4-4.5. The contacts of electrode arrays were clearly shown to locate in the scala tympani. There was a linear correlation between the 'A' value and cochlea height, and between the A value and actual electrode insertion length for the first 360° insertion depth.
目前高空间分辨率锥形束计算机断层扫描(CBCT)的实验装置在显示耳蜗的关键标志以确定耳蜗内电极触点位置方面具有优势,并且在人工耳蜗(CI)手术中具有临床应用潜力。
评估一种新开发的CBCT系统在确定人类颞骨中CI电极阵列和耳蜗形态变异方面的情况。
通过无创的圆窗膜插入,将标准电极、柔性尖端电极(Flex28)以及来自美敦力公司的具有36个触点的实验性电极阵列植入六具人类颞骨的耳蜗中。使用基于安装有Superior SXR 130 - 15 - 0.5 X射线管并结合铜和铝过滤的CBCT扫描仪的实验装置,对耳蜗进行900帧成像。
在所有颞骨中,耳蜗、蜗轴、骨螺旋板、圆窗龛和镫骨的标志平均在3.4 - 4.5的水平上得以显示。电极阵列的触点清晰显示位于鼓阶。在前360°插入深度方面,“A”值与耳蜗高度之间以及“A”值与实际电极插入长度之间存在线性相关性。