Lyon D S, Kaminski P F, Wheelock J B
Department of Obstetrics and Gynecology, Keesler Medical Center, Kesler AFB, Miss.
South Med J. 1989 Feb;82(2):190-2. doi: 10.1097/00007611-198902000-00011.
Of 35,937 gynecologic cytology specimens obtained from the cervix or vagina at our institution during a three-year period, 18 (0.05%) were reported as malignant; ten of these 18 (56%) positive results were due to carcinoma arising from sites other than the cervix or vagina. The site of the primary lesion was the endometrium in four patients, the ovary in three, the colon in one, and the breast in one; in one patient the site of the primary carcinoma was unknown. In our patient population a a positive Papanicolaou smear was more often indicative of a noncervical than a cervical malignancy. In addition to detecting preinvasive and invasive malignancies of the cervix and/or vagina, an annual cytologic smear may hasten the detection of extravaginal primary carcinomas.
在我们机构三年期间从宫颈或阴道获取的35937份妇科细胞学标本中，有18份（0.05%）报告为恶性；这18份阳性结果中有10份（56%）是由宫颈或阴道以外部位发生的癌所致。原发性病变部位在4例患者中为子宫内膜，3例为卵巢，1例为结肠，1例为乳腺；1例患者原发性癌的部位不明。在我们的患者群体中，巴氏涂片阳性更常提示非宫颈恶性肿瘤而非宫颈恶性肿瘤。除了检测宫颈和/或阴道的原位癌和浸润性恶性肿瘤外，每年进行细胞学涂片检查可能会加速阴道外原发性癌的检测。
