Benoit A G, Krepart G V, Lotocki R J
Am J Obstet Gynecol. 1984 Mar 1;148(5):690-4. doi: 10.1016/0002-9378(84)90775-0.
Cervical carcinoma is a disease which lends itself to prevention and diagnosis by cytologic screening. The results of previous Papanicolaou smears were obtained in 84 patients. Of 197 Papanicolaou smear results obtained prior to diagnosis of Stage I carcinoma, 63 (31%) were positive; and of 51 such smears obtained 1 year prior to diagnosis, 30 (59%) were positive. Possible explanations for negative screening prior to development of carcinoma are given. The need for centralized cytologic screening programs on a provincial basis is stressed.
宫颈癌是一种可通过细胞学筛查进行预防和诊断的疾病。我们获取了84例患者之前的巴氏涂片结果。在I期癌诊断之前获得的197份巴氏涂片结果中,63份(31%)呈阳性;而在诊断前1年获得的51份此类涂片结果中,30份(59%)呈阳性。文中给出了癌症发生前筛查呈阴性的可能解释。强调了在省级层面开展集中细胞学筛查项目的必要性。