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挪威奥斯陆一所监狱中纳洛酮分发的过量预防培训:初步研究。

Overdose prevention training with naloxone distribution in a prison in Oslo, Norway: a preliminary study.

机构信息

Norwegian Centre for Addiction Research, Institute of Clinical Medicine, University of Oslo, P.O. Box 1039 Blindern, 0315, Oslo, Norway.

出版信息

Harm Reduct J. 2017 Nov 21;14(1):74. doi: 10.1186/s12954-017-0200-z.

Abstract

BACKGROUND

Prison inmates face a ten times increased risk of experiencing a fatal drug overdose during their first 2 weeks upon release than their non-incarcerated counterparts. Naloxone, the antidote to an opioid overdose, has been shown to be feasible and effective when administered by bystanders. Given the particular risk that newly released inmates face, it is vital to assess their knowledge about opioid overdoses, as well as the impact of brief overdose prevention training conducted inside prisons.

METHODS

Prison inmates nearing release (within 6 months) in Oslo, Norway, voluntarily underwent a brief naloxone training. Using a questionnaire, inmates were assessed immediately prior to and following a naloxone training. Descriptive statistics were performed for main outcome variables, and the Wilcoxon signed-rank test was used to compare the participants' two questionnaire scores from pre-and post-training.

RESULTS

Participating inmates (n = 31) were found to have a high baseline knowledge of risk factors, symptoms, and care regarding opioid overdoses. Nonetheless, a brief naloxone training session prior to release significantly improved knowledge scores in all areas assessed (p < 0.001). The training appears to be most beneficial in improving knowledge regarding the naloxone, including its use, effect, administration, and aftercare procedures.

CONCLUSIONS

Given the high risk of overdosing that prison inmates face upon release, the need for prevention programs is critical. Naloxone training in the prison setting may be an effective means of improving opioid overdose response knowledge for this particularly vulnerable group. Naloxone training provided in the prison setting may improve the ability of inmates to recognize and manage opioid overdoses after their release; however, further studies on a larger scale are needed.

摘要

背景

在出狱后的头两周,监狱囚犯经历致命药物过量的风险比非监禁人员高出十倍。纳洛酮是阿片类药物过量的解毒剂,当由旁观者给药时,已被证明是可行且有效的。鉴于新出狱的囚犯面临的特殊风险,评估他们对阿片类药物过量的了解,以及在监狱内进行简短的过量预防培训的效果至关重要。

方法

挪威奥斯陆即将出狱(在 6 个月内)的囚犯自愿接受了简短的纳洛酮培训。使用问卷,在纳洛酮培训前后对囚犯进行评估。对主要结局变量进行描述性统计,使用 Wilcoxon 符号秩检验比较参与者培训前后的两份问卷得分。

结果

参与的囚犯(n=31)在阿片类药物过量的风险因素、症状和护理方面具有较高的基线知识水平。尽管如此,在出狱前进行短暂的纳洛酮培训课程显著提高了所有评估领域的知识得分(p<0.001)。培训似乎在提高关于纳洛酮的知识方面最有效,包括其用途、效果、给药和后续护理程序。

结论

鉴于监狱囚犯出狱后面临的高过量风险,预防计划的需求至关重要。监狱环境中的纳洛酮培训可能是提高这个特别脆弱群体对阿片类药物过量反应知识的有效手段。监狱环境中提供的纳洛酮培训可能会提高囚犯在出狱后识别和管理阿片类药物过量的能力;然而,还需要进一步进行更大规模的研究。

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