Montan S, Ingemarsson I
Department of Obstetrics and Gynecology, University of Lund, Sweden.
Am J Obstet Gynecol. 1989 Feb;160(2):283-8. doi: 10.1016/0002-9378(89)90426-2.
Intrapartum fetal heart rate patterns were investigated in pregnancies complicated by hypertension in a cohort study. The total number of live births was 2400 and the frequency of hypertension was 8.8%. The study group comprised 2023 normotensive and 200 hypertensive deliveries. Dates of all pregnancies were established at an ultrasound examination in week 17. Ominous intrapartum fetal heart rate patterns were significantly more common in hypertensive deliveries than in normotensive deliveries (20.5% versus 7.6%). The women with hypertension were compared with a group of control women matched for age, parity, induction of labor, and gestational week (20.5% versus 6.5%). In hypertensive women ominous fetal heart rate tracings were frequently associated with primiparity, induced labor, epidural block, delivery of a growth-retarded fetus, and beta 1-adrenergic receptor blockers. Ominous fetal heart rate patterns were less common in hypertensive women without these risk factors; still the significant differences in comparison with normotensive women remained. The hypertensive pregnancies accounted for no less than 21.0% of all ominous intrapartum fetal heart rate patterns, whereas 13% of all cases of ominous intrapartum fetal heart rate patterns could be attributed to the excess frequency in hypertensive pregnancies.
在一项队列研究中，对患有高血压的妊娠分娩期胎儿心率模式进行了调查。活产总数为2400例，高血压发生率为8.8%。研究组包括2023例血压正常和200例高血压分娩。所有妊娠日期均在第17周的超声检查时确定。分娩期胎儿心率异常模式在高血压分娩中比在血压正常分娩中明显更常见（分别为20.5%和7.6%）。将患有高血压的女性与一组年龄、产次、引产和孕周相匹配的对照女性进行比较（分别为20.5%和6.5%）。在患有高血压的女性中，胎儿心率异常描记图常与初产、引产、硬膜外阻滞、胎儿生长受限和β1肾上腺素能受体阻滞剂有关。没有这些危险因素的高血压女性中胎儿心率异常模式较少见；但与血压正常女性相比仍有显著差异。高血压妊娠占所有分娩期胎儿心率异常模式的不少于21.0%，而所有分娩期胎儿心率异常模式病例的13%可归因于高血压妊娠的高发生率。
