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本文引用的文献

1
Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice.自愿跑步运动可预防老年小鼠脓毒症引起的早期炎症和促凝反应。
Crit Care. 2017 Aug 8;21(1):210. doi: 10.1186/s13054-017-1783-1.
2
Challenges with Diagnosing and Managing Sepsis in Older Adults.老年人脓毒症诊断与管理面临的挑战。
Expert Rev Anti Infect Ther. 2016;14(2):231-41. doi: 10.1586/14787210.2016.1135052. Epub 2016 Jan 14.
3
Benefits of Regular Exercise on Inflammatory and Cardiovascular Risk Markers in Normal Weight, Overweight and Obese Adults.规律运动对正常体重、超重及肥胖成年人炎症和心血管风险标志物的益处
PLoS One. 2015 Oct 16;10(10):e0140596. doi: 10.1371/journal.pone.0140596. eCollection 2015.
4
Endothelial nitric oxide synthase in the microcirculation.微循环中的内皮型一氧化氮合酶。
Cell Mol Life Sci. 2015 Dec;72(23):4561-75. doi: 10.1007/s00018-015-2021-0. Epub 2015 Aug 25.
5
Animal models of aging research: implications for human aging and age-related diseases.衰老研究的动物模型：对人类衰老和与年龄相关疾病的影响。
Annu Rev Anim Biosci. 2015;3:283-303. doi: 10.1146/annurev-animal-022114-110829.
6
Sepsis in old age: review of human and animal studies.老年脓毒症：人类和动物研究综述。
Aging Dis. 2014 Apr 1;5(2):126-36. doi: 10.14336/AD.2014.0500126. eCollection 2014 Apr.
7
Impact of older age and nursing home residence on clinical outcomes of US emergency department visits for severe sepsis.老年和养老院居住对美国急诊科严重脓毒症就诊临床结局的影响。
J Crit Care. 2013 Oct;28(5):606-11. doi: 10.1016/j.jcrc.2013.03.018. Epub 2013 May 15.
8
Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly.老年严重脓毒症中免疫活性 T 细胞减少伴长时间淋巴细胞减少。
Crit Care Med. 2013 Mar;41(3):810-9. doi: 10.1097/CCM.0b013e318274645f.
9
Impact of physical activity on inflammation: effects on cardiovascular disease risk and other inflammatory conditions.体力活动对炎症的影响：对心血管疾病风险和其他炎症状况的影响。
Arch Med Sci. 2012 Nov 9;8(5):794-804. doi: 10.5114/aoms.2012.31614. Epub 2012 Nov 7.
10
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity.内皮型一氧化氮合酶、血管完整性与人类超长寿命。
Immun Ageing. 2012 Nov 15;9(1):26. doi: 10.1186/1742-4933-9-26.

年龄、运动与脓毒症结局。

Age, exercise, and the outcome of sepsis.

机构信息

Department of Medicine, Warren Alpert Medical School of Brown University, 593 Eddy St., Providence, RI, 02903, USA.

Lifespan Hospital System, Providence, RI, USA.

出版信息

Crit Care. 2017 Nov 23;21(1):286. doi: 10.1186/s13054-017-1840-9.

DOI:10.1186/s13054-017-1840-9
PMID:29169402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5701382/
Abstract

We report on the increasingly important need to diagnose and care for the elderly with sepsis as a distinct patient population. We share an overview of age-related changes in sepsis physiology and the potential role of exercise.See related research by Tyml et al., https://ccforum.biomedcentral.com/articles/10.1186/s13054-017-1783-1.

摘要

我们报告了一个日益重要的需求，即为老年人脓毒症患者作为一个独特的患者群体进行诊断和护理。我们分享了脓毒症生理学与年龄相关变化的概述，以及运动的潜在作用。参见 Tyml 等人的相关研究，https://ccforum.biomedcentral.com/articles/10.1186/s13054-017-1783-1。