Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil, Iran.
Department of Chemical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, 15875-4413, Iran; Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117585, Singapore.
Int J Biol Macromol. 2018 Apr 1;109:1219-1231. doi: 10.1016/j.ijbiomac.2017.11.119. Epub 2017 Nov 21.
Montmorillonite -copper oxide (MMT-CuO) nanocomposites were prepared by a facile and eco-friendly method and introduced into chitosan (Cs) matrix to enhance its optical, mechanical and antibacterial properties. The synthesized composites were characterized using diffuse reflectance spectroscopy (DRS), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and energy dispersive X-ray (EDX) spectroscopy. The antimicrobial activity of MMT-CuO nanocomposites showed more than 99% mortality against two Gram-negative bacterium (E.coli (PTCC 1270), P.aeruginosa (PTCC 1430)) and two Gram-positive bacterium (S.aureus (PTCC1112) B.cereus (PTCC- 1015)). The effect of weight fraction of MMT-CuO nanocomposites (1, 3 and 5% w/w) as antibacterial nanofiller on physical, optical, mechanical, microstructural, and antibacterial properties of chitosan films were evaluated. The obtained data showed that introducing small amount MMT-CuO to chitosan films could enhance the mechanical, antibacterial properties, and decreased both water solubility and UV transition with the lowest effect on the transparency of the films. The incorporation of 3% w/w MMT-CuO-90 nanocomposite into the films increased the tensile strong (TS), and elongation at break (E%) values 58.5% and 52.4%, respectively while reduced the water vapor permeability and oxygen permeability about 55% and 32%, respectively. CSG3MMT-CuO-90 films showed intense antibacterial activity against food borne pathogenic and more effective against S. aureus and B.cereus. than E.coli and P.aeruginosa.
蒙脱石-氧化铜（MMT-CuO）纳米复合材料采用简便、环保的方法制备，并引入壳聚糖（Cs）基体中，以提高其光学、机械和抗菌性能。采用漫反射光谱（DRS）、X 射线衍射（XRD）、场发射扫描电子显微镜（FESEM）和能谱（EDX）对合成的复合材料进行了表征。MMT-CuO 纳米复合材料的抗菌活性对两种革兰氏阴性菌（E.coli（PTCC 1270）、P.aeruginosa（PTCC 1430））和两种革兰氏阳性菌（S.aureus（PTCC1112）、B.cereus（PTCC-1015））的致死率超过 99%。评估了 MMT-CuO 纳米复合材料（1、3 和 5%w/w）作为抗菌纳米填料的重量分数对壳聚糖薄膜的物理、光学、机械、微观结构和抗菌性能的影响。结果表明，在壳聚糖薄膜中引入少量 MMT-CuO 可以提高机械性能和抗菌性能，同时降低水溶性和紫外透光率，对薄膜的透明度影响最小。将 3%w/w 的 MMT-CuO-90 纳米复合材料掺入薄膜中，可使拉伸强度（TS）和断裂伸长率（E%）分别提高 58.5%和 52.4%，而水蒸气透过率和氧气透过率分别降低约 55%和 32%。CSG3MMT-CuO-90 薄膜对食源性病原体表现出强烈的抗菌活性，对 S.aureus 和 B.cereus 的抗菌效果优于 E.coli 和 P.aeruginosa。
