van Mens P R, James J
J Oral Rehabil. 1979 Oct;6(4):337-44. doi: 10.1111/j.1365-2842.1979.tb00414.x.
A quantitative histological investigation was carried out on biopsy specimens taken from patients suffering from denture sore mouth. The results were compared with those obtained in investigations on denture and non-denture wearers. The sections were studied by standardized quantitative morphometric methods. After 4 years the denture bearing palatal epithelium from both groups, normal denture wearers and the patients suffering from denture sore mouth did not show changes in mean thickness of the epithelium as compared with the controls. The mitotic index in denture bearing epithelium from patients suffering from denture sore mouth was three times lower than in the epithelium of the normal denture wearers. The number of Langerhans cells correlated with the mitotic indices of the group of denture wearers and non-denture wearers. The group of denture sore mouth patients showing a low mitotic index showed a high number of Langerhans cells in their palatal epithelium. The three groups of patients investigated did not show differences in density of mast cells in the lamina propria of their palatal epithelium.
对义齿性口炎患者的活检标本进行了定量组织学研究。将结果与对戴义齿者和不戴义齿者的研究结果进行了比较。采用标准化定量形态计量学方法对切片进行研究。4年后，正常戴义齿者和义齿性口炎患者两组的义齿承托区腭上皮与对照组相比，上皮平均厚度未显示出变化。义齿性口炎患者义齿承托区上皮的有丝分裂指数比正常戴义齿者的上皮低三倍。朗格汉斯细胞数量与戴义齿组和不戴义齿组的有丝分裂指数相关。有丝分裂指数低的义齿性口炎患者组腭上皮中朗格汉斯细胞数量较多。所研究的三组患者腭上皮固有层中肥大细胞密度无差异。
