不同房室间期对双腔起搏器患者运动能力改善的生理重要性。
Physiological importance of different atrioventricular intervals to improved exercise performance in patients with dual chamber pacemakers.
作者信息
Haskell R J, French W J
机构信息
Department of Medicine, University of California, Los Angeles School of Medicine.
出版信息
Br Heart J. 1989 Jan;61(1):46-51. doi: 10.1136/hrt.61.1.46.
To determine the importance of different atrioventricular intervals during exercise in patients with dual chamber pacemakers, seven patients with complete heart block and sinus rhythm were exercised in different pacing modes and atrioventricular intervals: (a) ventricular inhibited (VVI) pacing with no synchronous atrial augmentation or rate responsiveness; (b) atrial synchronous ventricular or DDD pacing with a short mean (SD) atrioventricular interval of 66 (4) ms; and (c) DDD pacing with a long atrioventricular interval of 168 (12) ms. Pacing with a short or long atrioventricular interval gave similar maximum heart rates, oxygen uptake at the anaerobic threshold, end tidal pressure of carbon dioxide or oxygen pulse (a measure of stroke volume). Pacing with either a short or long atrioventricular interval produced a significantly higher oxygen consumption and anaerobic threshold and less lactate production than VVI pacing. During exercise a short atrioventricular interval does not provide a better cardiopulmonary performance than a long atrioventricular interval.
为确定双腔起搏器患者运动期间不同房室间期的重要性，对7例完全性心脏传导阻滞且有窦性心律的患者采用不同起搏模式和房室间期进行运动试验：(a)心室抑制(VVI)起搏，无同步心房增强或频率应答；(b)心房同步心室起搏或DDD起搏，平均(标准差)房室间期短，为66(4)毫秒；(c)DDD起搏，房室间期长，为168(12)毫秒。采用短或长房室间期起搏时，最大心率、无氧阈时的摄氧量、呼气末二氧化碳分压或氧脉搏(心搏量的一种测量指标)相似。采用短或长房室间期起搏时，与VVI起搏相比，耗氧量和无氧阈显著更高，乳酸生成更少。运动期间，短房室间期并不比长房室间期带来更好的心肺功能表现。
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