Sutton R, Morley C, Chan S L, Perrins J
Pacing Clin Electrophysiol. 1983 Mar;6(2 Pt 2):327-8. doi: 10.1111/j.1540-8159.1983.tb04368.x.
Over a five-year period, hemodynamic exercise capacity studies and a randomized controlled trial have been performed in a total of 50 patients. DVI vs. VVI pacing showed an increase in stroke work index (P less than 0.005) and a fall in left ventricular filling pressure (P less than 0.05) in 17 patients. VDD/DDD pacing vs. VVI showed an exercise capacity benefit in 44 patients (P less than 0.01) including 8 patients with sinus node disease and a lower peak heart rate (P less than 0.02). Maintenance of benefit was also shown of VDD/DDD pacing in the longer term (13 months) vs. acute (P - NS). The controlled trial VDD/DDD vs. VVI showed benefit in shortness of breath (P less than 0.01) and general well being (P less than 0.01). It is concluded that atrial synchronous ventricular pacing (VDD/DDD) is the mode of choice in suitable patients.
在五年期间,共对50名患者进行了血流动力学运动能力研究和一项随机对照试验。在17名患者中,DVI起搏与VVI起搏相比,每搏作功指数增加(P<0.005),左心室充盈压下降(P<0.05)。VDD/DDD起搏与VVI起搏相比,44名患者的运动能力得到改善(P<0.01),其中包括8名窦房结疾病患者,且峰值心率较低(P<0.02)。与急性情况相比,长期(13个月)的VDD/DDD起搏也显示出益处(P-无显著性差异)。VDD/DDD与VVI的对照试验显示,在呼吸急促(P<0.01)和总体健康状况(P<0.01)方面有改善。结论是,心房同步心室起搏(VDD/DDD)是适合患者的首选起搏模式。