Nagamoto Yasutsugu, Fujii Yuto, Morita Yuichi, Ueda Yusuke, Miyake Yasuko, Yamane Kenichi, Fujiwara Mai, Mito Shinji, Watari Yuichiro, Tamekiyo Hiromichi, Okimoto Tomokazu, Muraoka Yuji, Hayashi Yasuhiko
Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan.
Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan.
Indian Heart J. 2017 Nov-Dec;69(6):714-719. doi: 10.1016/j.ihj.2017.05.008. Epub 2017 May 23.
Ventricular fibrillation and atrial fibrillation are well-known arrhythmias in patients with Brugada syndrome. This study evaluated the characteristics of the atrial arrhythmogenic substrate using the signal-averaged electrogram (SAECG) in patients with Brugada syndrome.
SAECGs were performed during normal sinus rhythm in 23 normal volunteers (control group), 21 patients with paroxysmal atrial fibrillation (PAF; PAF group), and 21 with Brugada syndrome (Brugada group).
The filtered P wave duration (fPd) in the control, Brugada, and PAF groups was 113.9±12.9ms, 125.3±15.0ms, and 137.1±16.3ms, respectively. The fPd in the PAF group was significantly longer compared to that in the control and Brugada groups (p<0.05). The fPd in the Brugada group was significantly longer than that in the control group (p<0.05) and significantly shorter than that in the PAF group (p<0.05).
Patients with Brugada syndrome had abnormal P waves on the SAECG. The abnormal P waves on the SAECG in Brugada syndrome patients may have intermediate characteristics between control and PAF patients.
室颤和房颤是布加综合征患者中众所周知的心律失常。本研究使用信号平均心电图（SAECG）评估了布加综合征患者心房致心律失常基质的特征。
对23名正常志愿者（对照组）、21名阵发性房颤患者（PAF；PAF组）和21名布加综合征患者（布加综合征组）在正常窦性心律期间进行SAECG检查。
对照组、布加综合征组和PAF组的滤波P波时限（fPd）分别为113.9±12.9毫秒、125.3±15.0毫秒和137.1±16.3毫秒。PAF组的fPd显著长于对照组和布加综合征组（p<0.05）。布加综合征组的fPd显著长于对照组（p<0.05），且显著短于PAF组（p<0.05）。
布加综合征患者的SAECG上有异常P波。布加综合征患者SAECG上的异常P波可能具有介于对照组和PAF患者之间的中间特征。
