A Jabir, Mathew Anoop, Viswanathan Sunitha, S M Ashraf, Sebastian Placid, C K Prasannakumar, A George Koshy, Pisharody Sunil, Mathew Rony, Jeyasheelan L
Lisie Hospital, Kochi, Kerala, India.
MOSC Medical College, Kolencherry, Kerala, India.
Indian Heart J. 2017 Nov-Dec;69(6):777-783. doi: 10.1016/j.ihj.2017.05.025. Epub 2017 May 31.
ST-elevation myocardial infarction (STEMI) continues to be a major cause of cardiovascular mortality in Kerala, India. Timely primary percutaneous coronary intervention (PCI) is the recommended reperfusion strategy for STEMI. There is limited data on the safety, effectiveness, equity and efficiency of regional primary PCI services in India.
METHODS/DESIGN: The primary angioplasty registry of Kerala is a clinician-initiated prospective state-wide longitudinal hospital-based registry of patients undergoing primary PCI for STEMI. The registry aims to document the efficacy and safety of the real world use of primary PCI in Indian patients presenting with STEMI, in order to achieve regional adoption of global standard performance indicators. In addition, the registry would analyze procedural variations in the performance of primary PCI and assess its impact on relevant patient centered outcomes. We plan to enroll 6000 STEMI patients, undergoing primary PCI, across 48 hospitals. These patients would be followed up for a minimum of 1year.
The primary angioplasty registry of Kerala would help analyze the quality and outcomes of primary PCI services in Kerala, thereby yielding insights that can help limit unacceptable procedural variations in the performance of primary PCI. Identifying deviations from guideline based therapies can form the basis of quality improvement programs, which in turn will enable hospitals to achieve better patient outcomes.
在印度喀拉拉邦，ST段抬高型心肌梗死（STEMI）仍然是心血管疾病死亡的主要原因。及时进行直接经皮冠状动脉介入治疗（PCI）是STEMI推荐的再灌注策略。关于印度地区直接PCI服务的安全性、有效性、公平性和效率的数据有限。
方法/设计：喀拉拉邦直接血管成形术登记处是一个由临床医生发起的、全州范围内基于医院的前瞻性纵向登记处，登记接受STEMI直接PCI治疗的患者。该登记处旨在记录在现实世界中对患有STEMI的印度患者使用直接PCI的疗效和安全性，以便在区域内采用全球标准性能指标。此外，该登记处将分析直接PCI操作中的差异，并评估其对以患者为中心的相关结局的影响。我们计划在48家医院招募6000名接受直接PCI的STEMI患者。这些患者将至少随访1年。
喀拉拉邦直接血管成形术登记处将有助于分析喀拉拉邦直接PCI服务的质量和结局，从而得出有助于限制直接PCI操作中不可接受差异的见解。识别与基于指南的治疗方法的偏差可以构成质量改进计划的基础，进而使医院能够取得更好的患者结局。
