Li Tian, Feng Xiaoming, Lv Jianwei, Cai Tianyao, Wang Siyou
Acupuncture Department, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China.
The Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China.
Urology. 2018 Feb;112:69-73. doi: 10.1016/j.urology.2017.10.047. Epub 2017 Nov 22.
To compare the short-term efficacy of electrical pudendal nerve stimulation (EPNS) vs anogenital electrical stimulation (AES) for neurogenic lower urinary tract disease.
Sixty eligible participants were randomized at a ratio of 2:1 to the test group of 40 patients and the control group of 20. The test group was treated with EPNS and the control group was treated with AES. After 12 sessions of treatment, therapeutic effects were evaluated based on self-assessed questionnaire scores. All patients with a residual urine volume >50 mL were also assessed by the post-treatment residual urine volume.
At the end of treatment, the median symptom score and the quality of life score were 11 (range 3-23) and 4.26 (range 1.00-5.81) in the test group, and the median post-treatment residual urine volume was 46 (range 0-223) mL. By contrast, the median severity of symptoms and quality of life scores were 15 (range 8-33) and 3.84 (range 0.89-5.84) in the control group, and the median post-treatment residual urine volume was 105 (range 28-340) mL. Significant differences between the test group and the control group could be observed in the post-treatment symptom score, the quality of life score, and the residual urine volume (with P = .005, P <.001, P = .02, respectively).
Compared with AES, EPNS is more effective in treating neurogenic lower urinary tract disease in the short term.
比较阴部神经电刺激（EPNS）与肛门生殖器电刺激（AES）治疗神经源性下尿路疾病的短期疗效。
60名符合条件的参与者按2:1的比例随机分为40例患者的试验组和20例患者的对照组。试验组采用EPNS治疗，对照组采用AES治疗。治疗12次后，根据自我评估问卷评分评估治疗效果。所有残余尿量>50 mL的患者还通过治疗后的残余尿量进行评估。
治疗结束时，试验组的症状评分中位数和生活质量评分分别为11（范围3 - 23）和4.26（范围1.00 - 5.81），治疗后的残余尿量中位数为46（范围0 - 223）mL。相比之下，对照组的症状严重程度中位数和生活质量评分分别为15（范围8 - 33）和3.84（范围0.89 - 5.84），治疗后的残余尿量中位数为105（范围28 - 340）mL。试验组与对照组在治疗后的症状评分、生活质量评分和残余尿量方面存在显著差异（P分别为0.005、<0.001、0.02）。
与AES相比，EPNS在短期内治疗神经源性下尿路疾病更有效。
