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东田纳西州的新生儿戒断综合征:阿巴拉契亚一个地区母婴的特征及危险因素

Neonatal Abstinence Syndrome in East Tennessee: Characteristics and Risk Factors among Mothers and Infants in One Area of Appalachia.

作者信息

Erwin Paul C, Meschke Laurie L, Ehrlich Samantha F, Lindley Lisa C

出版信息

J Health Care Poor Underserved. 2017;28(4):1393-1408. doi: 10.1353/hpu.2017.0122.

Abstract

OBJECTIVE

To describe the epidemiology of neonatal abstinence syndrome (NAS) in a 16-county Appalachian area of eastern Tennessee.

METHODS

The Tennessee Surveillance System for NAS provided data on maternal sources of opioids. Data linking hospital discharge diagnosis for NAS to birth certificate data allowed us to compare maternal, delivery, and infant characteristics for NAS births with those for non-NAS births.

RESULTS

There were 339 cases of NAS in 2013 and 367 in 2014, for NAS rates of 25.5 and 28.5 per 1,000 live births, respectively. When compared with the state overall, mothers of NAS infants in eastern Tennessee were more likely to use opioids that had been prescribed to another person. There were numerous maternal, infant, and delivery characteristics that were significantly different for NAS births compared with non-NAS births.

CONCLUSION

Neonatal abstinence syndrome is epidemic in the eastern Tennessee area of Appalachia, with unique maternal and infant characteristics that have important implications for primary, secondary, and tertiary prevention.

摘要

目的

描述田纳西州东部阿巴拉契亚地区16个县新生儿戒断综合征(NAS)的流行病学情况。

方法

田纳西州NAS监测系统提供了阿片类药物母体来源的数据。将NAS的医院出院诊断数据与出生证明数据相链接,使我们能够比较NAS出生婴儿与非NAS出生婴儿的母体、分娩和婴儿特征。

结果

2013年有339例NAS病例,2014年有367例,NAS发生率分别为每1000例活产25.5例和28.5例。与全州总体情况相比,田纳西州东部NAS婴儿的母亲更有可能使用他人开具的阿片类药物。与非NAS出生相比,NAS出生在许多母体、婴儿和分娩特征方面存在显著差异。

结论

新生儿戒断综合征在阿巴拉契亚地区的田纳西州东部呈流行态势,其独特的母体和婴儿特征对一级、二级和三级预防具有重要意义。

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