Choi Jae Woong, Kim Kyung Hwan, Lim Su Chan, Kim Sue Hyun, Sohn Suk Ho, Lee Yeiwon, Hwang Ho Young
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea.
Korean J Thorac Cardiovasc Surg. 2020 Dec 5;53(6):325-331. doi: 10.5090/kjtcs.19.075.
We evaluated the association between tricuspid annular dilatation and the development of moderate or severe tricuspid regurgitation (TR). Additionally, we determined the optimal tricuspid annular dilatation threshold to use as an indicator for tricuspid annuloplasty in patients with less-than-moderate functional TR (FTR).
Between August 2007 and December 2014, 227 patients with less-than-moderate TR underwent mitral valve surgery without a tricuspid valve (TV) procedure. The TV annular diameter was measured via transthoracic echocardiography. The TV annular index (TVAI) was calculated as the TV annular diameter divided by the body surface area. The mean duration of echocardiographic follow-up was 42.0 months (interquartile range, 9.3-66.6 months).
Eight patients (3.5%) developed moderate or severe TR. The rate of freedom from development of moderate or severe TR at 5 years was 96.2%. TV annular diameter, left atrial diameter, preoperative atrial fibrillation, and TVAI were found to be associated with the development of moderate or severe TR in the univariate analysis. A cut-off TVAI value of 19.8 mm/m was found to predict the development of moderate or severe TR, and a significant difference was observed in the development of TR of this severity based on this cut-off (p<0.001).
The progression of TR was not infrequent in patients with untreated lessthan- moderate FTR. An aggressive treatment approach can be helpful to prevent the progression of FTR for patients with risk factors, especially TVAI greater than 19.8 mm/m.
我们评估了三尖瓣环扩张与中度或重度三尖瓣反流(TR)发生之间的关联。此外,我们确定了最佳三尖瓣环扩张阈值,以作为功能不全程度低于中度的三尖瓣反流(FTR)患者进行三尖瓣环成形术的指标。
2007年8月至2014年12月期间,227例功能不全程度低于中度的TR患者接受了二尖瓣手术,未进行三尖瓣(TV)手术。通过经胸超声心动图测量TV环直径。计算TV环指数(TVAI),即TV环直径除以体表面积。超声心动图随访的平均持续时间为42.0个月(四分位间距为9.3 - 66.6个月)。
8例患者(3.5%)发生了中度或重度TR。5年时无中度或重度TR发生的比率为96.2%。在单因素分析中,发现TV环直径、左心房直径(LA)、术前心房颤动和TVAI与中度或重度TR的发生相关。发现TVAI值为19.8 mm/m可预测中度或重度TR的发生,基于此临界值观察到该严重程度的TR发生存在显著差异(p<0.001)。
未经治疗的功能不全程度低于中度的FTR患者中TR进展并不罕见。对于有危险因素的患者,尤其是TVAI大于19.8 mm/m的患者,积极的治疗方法可能有助于预防FTR进展。