Clinical Trials Group, School of Oral and Dental Sciences, University of Bristol, Lower Maudlin Street, Bristol BS1 2LY, UK.
Unilever Oral Care, Quarry Road East, Bebington, Wirral CH63 3JW, UK.
Dent Mater. 2018 Feb;34(2):355-362. doi: 10.1016/j.dental.2017.11.017. Epub 2017 Nov 24.
Previous work has shown the effectiveness of a newly developed interproximal model to differentiate between the amount of remineralization caused by toothpastes used with or without a dual-phase gel treatment system containing calcium silicate, sodium phosphate salts and fluoride to repair acid-softened enamel. The aim of this study was to utilize the same interproximal model to identify how effective calcium silicate phosphate toothpastes are at reducing surface softening in the early stages of erosion. The model was also used to identify the effect of increasing the frequency of acid exposure on the reduction in surface hardness.
Human enamel specimens were prepared and mounted in an interproximal face-to-face arrangement and exposed to a cycling regime of whole human saliva, treatment, artificial saliva and 1% citric acid pH 3.75. Specimens were measured by surface microhardness at baseline and after three and seven days. The frequency of acid exposure was increased from 2 to 4 cycles a day for the second part of the study.
The results showed that specimens treated with the calcium silicate phosphate toothpastes softened less than those treated with control fluoridated or non-fluoride toothpastes at each time point and following an increase in the frequency of acid exposure.
This work has demonstrated how an interproximal model can also be successfully used to determine differences in the erosion protection of various treatments as well as determining how they perform when the frequency of acid exposure is increased.
先前的研究表明,一种新开发的邻面模型在区分使用或不使用含有硅酸钙、磷酸钠盐和氟化物的双相凝胶处理系统的牙膏引起的再矿化量方面是有效的,以修复酸软化的牙釉质。本研究的目的是利用相同的邻面模型来确定硅酸钙磷酸盐牙膏在减少早期侵蚀过程中表面软化的效果。该模型还用于确定增加酸暴露频率对表面硬度降低的影响。
制备人牙釉质标本,以邻面面对面的方式安装,并暴露于全人唾液、处理液、人工唾液和 1%柠檬酸 pH3.75 的循环处理中。标本在基线和第 3 天和第 7 天通过表面显微硬度进行测量。在研究的第二部分,酸暴露的频率从每天 2 次增加到 4 次。
结果表明,与用对照氟化或非氟化物牙膏处理的标本相比,在用硅酸钙磷酸盐牙膏处理的标本在每个时间点以及在酸暴露频率增加后软化程度较小。
这项工作表明,邻面模型也可成功用于确定各种处理方法的防侵蚀效果差异,以及在增加酸暴露频率时它们的表现。