Dornblaser Emily K
College of Pharmacy, University of New England, Portland, ME.
Curr Pharm Teach Learn. 2017 Jan-Feb;9(1):95-100. doi: 10.1016/j.cptl.2016.08.042. Epub 2016 Nov 15.
Pharmacokinetic (PK) calculations are an important competency for pharmacy students, however, there is little to guide which medications should be included in pharmacy curricula. Additionally, many new medications require therapeutic drug monitoring (TDM)-but not PK calculations-to ensure safe use. The objectives of this study were to quantify which medications are most frequently encountered by pharmacy students during advanced pharmacy practice experiences (APPE's) and to what extent PK calculations or TDM were completed by students while on APPE's at the University of New England.
Fourth-year students were surveyed upon completion of their advanced pharmacy practice experiences (APPE's).
Pharmacokinetic calculations occurred most frequently on institutional rotations. Vancomycin and aminoglycosides were the two most common medications pharmacy students were asked to perform PK calculations for while on APPE's. Therapeutic drug monitoring occurred most frequently on institutional rotations. Therapeutic drug monitoring also occurred more often than pharmacokinetic monitoring on ambulatory care rotations.
Pharmacokinetic calculations as well as therapeutic drug monitoring requiring no calculations were both commonly encountered by student pharmacists while on APPE rotations. Changes to clinical guidelines have impacted the types of medications students are expected to have proficiency with, and more broadly defined therapeutic drug monitoring competencies may be important for ambulatory care APPE's.
药代动力学(PK)计算是药学专业学生的一项重要技能,然而,关于哪些药物应纳入药学课程的指导却很少。此外,许多新药需要治疗药物监测(TDM)——而不是PK计算——以确保安全使用。本研究的目的是量化药学专业学生在高级药学实践经验(APPE)期间最常遇到的药物,以及新英格兰大学的学生在进行APPE时完成PK计算或TDM的程度。
四年级学生在完成高级药学实践经验(APPE)后接受调查。
药代动力学计算在机构轮转中出现得最为频繁。万古霉素和氨基糖苷类是药学专业学生在进行APPE时被要求进行PK计算的两种最常见药物。治疗药物监测在机构轮转中出现得最为频繁。在门诊护理轮转中,治疗药物监测也比药代动力学监测更常出现。
学生药剂师在进行APPE轮转时,药代动力学计算以及无需计算的治疗药物监测都很常见。临床指南的变化影响了学生预期要熟练掌握的药物类型,更广泛定义的治疗药物监测能力对于门诊护理APPE可能很重要。