Zou Zi-Jun, Liang Jia-Yu, Liu Zhi-Hong, Gao Rui, Lu Yi-Ping
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Department of Urology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China.
Int J Impot Res. 2018 Feb;30(1):1-7. doi: 10.1038/s41443-017-0002-6. Epub 2017 Nov 27.
Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel treatment for erectile dysfunction (ED). Its ability to improve erectile function has been shown in patients with vasculogenic ED by many randomized-controlled trials against sham procedures. However, the role of LI-ESWT in ED caused by radical prostatectomy (RP) is still questionable because this type of ED was excluded from nearly all clinical studies; it has been investigated in only a few small single-arm trials. This review summarizes preclinical studies on mechanisms of action of LI-ESWT for ED and neurological diseases to explore the potential of this treatment for nerve-impaired ED after RP.
低强度体外冲击波疗法（LI-ESWT）是一种治疗勃起功能障碍（ED）的新型疗法。许多针对假手术的随机对照试验已表明，该疗法能够改善血管性ED患者的勃起功能。然而，LI-ESWT在根治性前列腺切除术（RP）所致ED中的作用仍存在疑问，因为几乎所有临床研究都将这类ED排除在外；仅有少数小型单臂试验对其进行了研究。本综述总结了LI-ESWT治疗ED和神经疾病作用机制的临床前研究，以探索该疗法对RP后神经损伤性ED的治疗潜力。
