Baylor College of Medicine, Houston, TX, USA.
Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA; Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
Sex Med Rev. 2018 Oct;6(4):624-630. doi: 10.1016/j.sxmr.2018.01.002. Epub 2018 Mar 22.
Vasculogenic erectile dysfunction (ED) is one of the leading causes of male sexual dysfunction. In the past decade, multiple studies have examined the use of low-intensity extracorporeal shockwave therapy (Li-ESWT) for the treatment of ED.
Investigate the efficacy of Li-ESWT for the treatment of ED.
We reviewed the published literature, including randomized controlled trials (RCTs), meta-analyses, and select single-arm studies on the use of Li-ESWT for the treatment of ED.
Changes in International Index of Erectile Function scores were evaluated in patients undergoing Li-ESWT.
There is no consensus from RCTs on the efficacy of Li-ESWT for the treatment of ED. Published meta-analyses have shown significant improvement in International Index of Erectile Function-erectile function domain scores in men undergoing Li-ESWT, especially when compared to men receiving sham treatment. However, differences in treatment protocols limit the generalizability of these findings. Li-ESWT may be more beneficial in cases of mild ED or when combined with phosphodiesterase type 5 inhibitors in men with moderate to severe ED. The role of Li-ESWT in the treatment of non-vasculogenic ED remains poorly defined.
Li-ESWT could be beneficial in specific sub-sets of men with vasculogenic ED. However, future RCTs should attempt to optimize treatment protocols and have more stringent inclusion criteria to confirm these findings. Rizk PJ, Krieger JR, Kohn TP, et al. Low-Intensity Shockwave Therapy for Erectile Dysfunction. Sex Med Rev 2018;6:624-630.
血管性勃起功能障碍（ED）是男性性功能障碍的主要原因之一。在过去的十年中，多项研究已经检查了低强度体外冲击波疗法（Li-ESWT）治疗 ED 的应用。
研究 Li-ESWT 治疗 ED 的疗效。
我们回顾了已发表的文献，包括随机对照试验（RCT）、荟萃分析以及关于 Li-ESWT 治疗 ED 的选择单臂研究。
评估接受 Li-ESWT 治疗的患者的国际勃起功能指数评分的变化。
RCT 对 Li-ESWT 治疗 ED 的疗效没有共识。已发表的荟萃分析显示，接受 Li-ESWT 的男性的国际勃起功能指数-勃起功能域评分有显著改善，尤其是与接受假治疗的男性相比。然而，治疗方案的差异限制了这些发现的普遍性。Li-ESWT 可能对轻度 ED 或在中重度 ED 男性中与磷酸二酯酶 5 抑制剂联合使用时更有益。Li-ESWT 在治疗非血管性 ED 中的作用仍定义不明确。
Li-ESWT 可能对特定的血管性 ED 男性亚组有益。然而，未来的 RCT 应尝试优化治疗方案并制定更严格的纳入标准，以证实这些发现。Rizk PJ, Krieger JR, Kohn TP, 等。低强度冲击波治疗勃起功能障碍。性医学评论 2018;6:624-630。
