Palacio-Cardona John, Caicedo Borrero Diana María
Student Welfare Service - Health Area, Santiago de Cali University.
Support for Research, Academic, Scientific and Technological Services (SEACIT), Cali, Colombia.
Int J Womens Health. 2017 Nov 16;9:835-842. doi: 10.2147/IJWH.S139289. eCollection 2017.
Acne vulgaris is the most common skin disease. It affects the young adult female population and generates great impact on physical and mental health. One of the treatments with good results for affected women is combined oral contraceptive pills (COCPs). The aim of this study was to determine the clinical effect of facial acne management with ethinylestradiol 20 µg/dienogest 2 mg in a cohort of Colombian adult women. A cohort of 120 female university students was followed for 12 months. These participants were enrolled in the Sexual and Reproductive Health Program of the Santiago de Cali University. This cohort admitted women between 18 and 30 years old who had chosen to start birth control with ethinylestradiol 20 µg/dienogest 2 mg COCPs, did not have contraindi cations to the use of COCPs, and had been diagnosed with acne. Monthly monitoring of facial acne lesion count was performed. Relative changes in facial lesion count were identified. At the end of follow-up, the percentage of reduction of lesions was 94% and 23% of women had a 100% reduction in acne lesions. In conclusion, the continued use of the ethinylestradiol 20 µg/dienogest 2 mg COCPs reduced inflammatory and non-inflammatory acne lesions in reproductive-age women between 18 and 30 years of age with no severe acne.
寻常痤疮是最常见的皮肤病。它影响年轻成年女性群体，对身心健康产生重大影响。对患病女性效果良好的治疗方法之一是复方口服避孕药（COCPs）。本研究的目的是确定在一组哥伦比亚成年女性中使用炔雌醇20μg/地诺孕素2mg治疗面部痤疮的临床效果。对120名女大学生进行了为期12个月的随访。这些参与者参加了卡利大学圣地亚哥分校的性与生殖健康项目。该队列纳入了18至30岁之间选择开始使用炔雌醇20μg/地诺孕素2mg复方口服避孕药进行避孕、没有使用复方口服避孕药的禁忌证且已被诊断为痤疮的女性。每月对面部痤疮皮损计数进行监测。确定面部皮损计数的相对变化。随访结束时，皮损减少百分比为94%，23%的女性痤疮皮损减少100%。总之，持续使用炔雌醇20μg/地诺孕素2mg复方口服避孕药可减少18至30岁无重度痤疮的育龄女性的炎性和非炎性痤疮皮损。
